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Richard U. Light and Hazel R. Prentice

indicates that a good selection for neurosurgery is a solution containing 100 units (Upjohn) * per cc. Since the thrombin as packaged contains 1500 units per vial, the addition of 15 cc. physiological salt solution to the vial yields this result, and the amount is generally adequate for completing a major neurosurgical procedure; only occasionally does a second vial need to be opened. Fig. 1. Three pieces of gelatin sponge originally of equal size (15 mm. cube). (A) The dry material. (B) Reduction of volume when dampened with water and squeezed out. (C

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Arthur B. Soule Jr.

W ith the high incidence of injuries to the central and peripheral nervous system sustained in this war, a volume of neurosurgical material has become available for study. Late effects of spinal cord and peripheral nerve damage are still not thoroughly understood and it is obvious that treatment of patients with lesions of this type cannot be delayed until such additional knowledge is acquired. It therefore seems justifiable to record any observations made that may shed a certain amount of light on this only partially explored field. With this purpose in mind

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Mac V. Edds Jr.

greatly reduced numbers, and their growth is so impeded that even after one year, their combined volume is still less than that of the fibers originally fixed. These results pertain to nerves up to 1.5 mm. in diameter and further tests must decide whether the method is equally effective in larger nerves. A preliminary study of sections of a cat sciatic nerve that had been capped with methacrylate showed that the epineurium acted as a barrier to the penetration of acetone and that the best fixation occurred at the cut surface of the nerve. This indicates that the

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Arthur D. Ecker

; Staphylococcus albus, 17; Streptococcus viridans, 9; non-hemolytic streptococcus, 9; gram-negative bacilli, 6; Micrococcus tetragenus, 4; and Clostridium, 2 cases. Surprisingly, there were no hemolytic streptococci in this series. The gram-negative bacilli were always found in association with coccus forms. From the study of the x-ray films and findings at operation an attempt was made to estimate the number of cubic centimeters of brain destruction in each case. The figures range from 5 to 250 cc. However, this estimated volume of brain tissue destroyed had no apparent

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Intracranial Angiography

I. The Diagnosis of Vascular Lesions

Carl F. List and Fred J. Hodges

patient entered the hospital because of right frontotemporal and orbital pain of 3 months' duration, occasionally associated with nausea and vomiting. In recent weeks she had developed diplopia. When blood pressure and pulse volume were tested, striking differences between the right and left sides were observed. Blood pressure in the right arm was 200/100; in the left arm 158/90. Carotid pulse was faint on the right; powerful on the left. A loud systolic bruit, best heard over the left carotid, somewhat more faintly over the aorta, could not be followed into the skull

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Benjamin B. Whitcomb and George M. Wyatt

syringe to overcome the effects of gravity. This gentle pull is continued until fluid streams up through the pantopaque without further increase in the volume of pantopaque in the syringe. The patient is again fluoroscoped and any remaining oil centered to the needle point. It may be necessary to again roll the patient to one side or the other to accomplish perfect centering. The aspiration procedure is repeated, until no further oil can be seen fluoroscopically. The needle is then withdrawn and the needle site slightly massaged. If there is any bleeding at the needle

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W. F. Windle, W. A. Rambach Jr., M. I. Robert de Ramirez De Arellano, R. A. Groat and R. F. Becker

the concern of the present report. Guinea pigs were used for this study because methods of producing concussion had been perfected and histopathological changes in the brain had been most carefully worked out in this species. The first task was to devise an accurate method for detecting small changes in water content of the brain which might be encountered after concussion. The brain was placed in a previously tared beaker and weighed. It was immediately covered with 25 cc. of acetone under which it was subdivided into pieces of approximately 2 volume to

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William H. Bridgers

. A sterile dairy thermometer is kept in the irrigating can in order to afford a temperature of 100° to 103°F. Initial filling is obtained by pressure on the bulb, which when released will draw fluid up from the can, filling the bulb and displacing the contained air. The bulb being used at the present time ( Fig. 1 ) has a volume of 50 cc. The force of the stream is regulated by the amount of pressure on the bulb. If constant irrigation is desired, raising the irrigating can higher than the operative field will cause a constant flow of fluid from the tip of the

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Henry A. Shenkin and Charles R. Perryman

study is shown in Fig. 1, A and B . Fig. 1. Case 1 . (A and B) Ventriculogram of an 18-year-old man who had symptoms of a posterior fossa lesion for 3 months. In the postero-anterior and left lateral horizontal positions, the lateral and 3rd ventricles are dilated to approximately twice their normal volume. The foramina of Monro and the aqueduct of Sylvius also are dilated. The shadow of the 4th ventricle is not visible. (C and D) Ventriculo-encephalogram 13 months after operative removal of a cerebellar medulloblastoma, showing little dilatation of the

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Miguel Prados and William C. Gibson

publish the Archivos Españoles de Oncología in which the research work of the Institute was reported. In 1933, on the occasion of the International Cancer Congress in Madrid, del Río published a beautifully illustrated monograph, Tumores del Sistema Nervioso . This comprehensive volume summarized his contributions to systematic neuropathology, but it does not contain any of his work on normal histology or experimental cytology. In 1937, while the Luftwaffe was destroying the University City in Madrid, a German scientific publisher asked permission to publish a