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Anna Lo Presti, Alexander G. Weil and John Ragheb

subsequent cerebral edema. 8 , 9 , 12 , 16 Finally, increasing levels of inspired CO 2 during commercial flights may lead to cerebral vasodilation and increased ICP. 7 , 17 In contrast, an overdrainage mechanism may also be responsible for producing symptoms. Many contemporary valves use Delta Chamber (Medtronic PS Medical) antisiphon devices (ASDs), which have a mobile membrane that moves toward or away from the control orifice when the pressure inside the shunt falls below or rises above atmospheric pressure, respectively. 5 When atmospheric pressure is lower, less

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between the two forms of treatment emerge. Neurosurg Focus Neurosurgical Focus FOC 1092-0684 American Association of Neurological Surgeons 2015.3.FOC-DSPNABSTRACTS 103. A Prospective, Multi-Center Assessment of the Best Versus Worst Clinical Outcomes for Adult Spinal Deformity (ASD) Surgery Justin S. Smith , MD PhD , Christopher I. Shaffrey , MD FACS , Virginie Lafage , PhD , Frank Schwab , MD, PhD , Themistocles Protopsaltis , MD , Eric Klineberg , MD , Munish

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Guy Matgé, Christophe Berthold, Vimal Raj Nitish Gunness, Ardian Hana and Frank Hertel

T he gold standard treatment for cervical disc disease is anterior cervical decompression and fusion (ACDF). The well-documented potential complications of ACDF, including symptomatic adjacent-segment disease (ASD), pseudarthrosis, graft donor site morbidity, and instrumentation-related problems have led to the search for motion-preserving alternatives that will provide adequate motion segment stabilization while eliminating the problems encountered with ACDF. 4 , 10 , 14 , 15 , 18 , 19 Recent results of several multicenter, prospective, randomized trials

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Perioperative Care A8 A8 Copyright held by the American Association of Neurological Surgeons. You may not sell, republish, or systematically distribute any published materials without written permission from JNSPG. 2015 Introduction Revision surgery for adjacent segment disease (ASD) has been shown to improve quality of life (QOL) in a cost-effective manner. However, the QOL and financial implications of developing ASD have not been well described in the literature. Methods Individuals with ASD were matched to control patients without ASD that

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Paul Park, Michael Y. Wang, Virginie Lafage, Stacie Nguyen, John Ziewacz, David O. Okonkwo, Juan S. Uribe, Robert K. Eastlack, Neel Anand, Raqeeb Haque, Richard G. Fessler, Adam S. Kanter, Vedat Deviren, Frank La Marca, Justin S. Smith, Christopher I. Shaffrey, Gregory M. Mundis Jr. and Praveen V. Mummaneni

, including adult spinal deformity (ASD). Anand et al. 3 initially reported the feasibility of applying several different MIS techniques to treat symptomatic lumbar scoliosis. Subsequent reports have all confirmed successful MIS treatment of ASD. 5 , 17 , 21 , 24 These studies, however, have been limited by the relatively small numbers of patients evaluated, as well as the lack of focus on sagittal alignment and spinopelvic parameters, which are factors known to significantly impact long-term disability. 12 , 18 In addition, there has been no uniform MIS technique or

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Lee Onn Chieng, Karthik Madhavan and Steven Vanni

* Cervical Infection Cardiac Failure/MI Dysphagia CSF Leak Pseudarthrosis SAS/ASD Ranawat et al., 1979 7.1% 7.1% NR NR NR NR 4/28 14.3 Thompson & Meyer, 1985 NR 8.3% NR NR NR NR 8.3% NR Larsson & Toolanen, 1986 NR 2.9% NR NR NR NR 14% NR Clark et al., 1989 NR 7.3% 7.3% 2.4% NR NR NR NR Santavirta et al., 1991 5.3% 2.6% 2.6% 7.9% NR NR NR NR Chan et al., 1992 5.3% 5.3% 5.3% 5.3% 5.3% NR NR NR Eyres et al., 1998 NR NR 3.8% NR NR NR

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Justin K. Scheer, Justin S. Smith, Aaron J. Clark, Virginie Lafage, Han Jo Kim, John D. Rolston, Robert Eastlack, Robert A. Hart, Themistocles S. Protopsaltis, Michael P. Kelly, Khaled Kebaish, Munish Gupta, Eric Klineberg, Richard Hostin, Christopher I. Shaffrey, Frank Schwab, Christopher P. Ames and the International Spine Study Group

I ndividuals who have adult spinal deformity (ASD) typically experience pain and disability. 2 , 14 , 26 , 28 , 29 The pain typically affects the back, legs, or both, and its etiology is multifactorial. 26 , 28 , 29 Over the last decade, most research into ASD has focused on patient-reported outcomes and on general measures of health status and function, such as the Oswestry Disability Index (ODI), the 36-Item Short Form Health Survey (SF-36), and the Scoliosis Research Society 22-question Questionnaire (SRS-22). However, pain is the primary concern for

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Albert P. Wong, Zachary A. Smith, Alexander T. Nixon, Cort D. Lawton, Nader S. Dahdaleh, Ricky H. Wong, Brenda Auffinger, Sandi Lam, John K. Song, John C. Liu, Tyler R. Koski and Richard G. Fessler

-time surgery. Diagnoses included spondylosis, spondylolisthesis, pseudarthrosis, adjacent-segment disease (ASD), spondylolysis, recurrent disc herniation, and previous failed surgery. Excluded patients included those who had had long-construct scoliosis correction, trauma, posterior lumbar interbody fusion, anterior lumbar interbody fusion (ALIF), extreme-lateral interbody fusion, direct lateral interbody fusion, combined procedures, open TLIF, tumor, or previous surgical infection. Demographic data on these 513 patients were collected. Age, sex, preoperative diagnosis

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Taemin Oh, Justin K. Scheer, Robert Eastlack, Justin S. Smith, Virginie Lafage, Themistocles S. Protopsaltis, Eric Klineberg, Peter G. Passias, Vedat Deviren, Richard Hostin, Munish Gupta, Shay Bess, Frank Schwab, Christopher I. Shaffrey and Christopher P. Ames

A dult spinal deformity (ASD) is a pathological condition defined as spinal malalignment in the axial, coronal, or sagittal plane and is derivative of congenital, iatrogenic, degenerative, or idiopathic etiology. 30 The restoration of sagittal alignment, as established by the sagittal vertical axis (SVA; target < 5 cm) and pelvic tilt (PT; target < 20°) on sagittal radiography, is important in surgical deformity correction. 6 , 21 , 22 Although coronal plane correction also has clinical relevance, sagittal corrections appear to have greater importance, 5

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Saurabh Sinha, Robert A. McGovern and Sameer A. Sheth

control . Dev Psychopathol 18 : 77 – 98 , 2006 69 Port RG , Gandal MJ , Roberts TPL , Siegel SJ , Carlson GC : Convergence of circuit dysfunction in ASD: a common bridge between diverse genetic and environmental risk factors and common clinical electrophysiology . Front Cell Neurosci 8 : 414 , 2014 70 Pugliese L , Catani M , Ameis S , Dell’Acqua F , Thiebaut de Schotten M , Murphy C , : The anatomy of extended limbic pathways in Asperger syndrome: a preliminary diffusion tensor imaging tractography study . Neuroimage 47