✓ A modification of the fibrin plate method was developed to measure fibrinolysis in patients with subarachnoid hemorrhage and those receiving antifibrinolytic agents. During the past 2 years, 21 patients with ruptured intracranial aneurysms received epsilon aminocaproic acid. Plasma and cerebrospinal fluid were monitored in 15 of these patients. Dosage factors, duration of action, and complications of therapy are presented. Fibrinolysis in normal plasma and cerebrospinal fluid is also discussed.
Robert R. Smith and John J. Upchurch
Robert R. Smith and Andrew D. Parent
✓ A case of a giant anterior cerebral artery fusiform aneurysm is presented. The lesion was treated by primary excision of the involved segment with an end-to-end anastomosis of the proximal-distal segments of the anterior cerebral artery. It is believed that this technique has not been reported previously for lesions involving major intracranial arteries.
Ben R. Clower, David M. Sullivan and Robert R. Smith
✓ A micro-corrosion technique was used to demonstrate an extensive vasa vasorum network in extracranial vessels but did not reveal this system in intracranial vessels of comparable size in three species of animals. The absence of a vasa vasorum network in cerebral vessels may result in a higher level of susceptibility to periarterial abnormalities, such as cerebral vasospasm secondary to subarachnoid hemorrhage.
Robert R. Smith, C. Jay Kees and Ira D. Hogg
✓ A 22-year-old man admitted to the hospital following a head injury was found to have agenesis of the right internal carotid artery with a large carotid-cavernous anastamosis at the level of the dorsum sellae.
Report of two cases
Robert A. Sanford, Jose Bebin and R. Wayne Smith
✓ The authors present the cases of two young adults with low-grade astrocytomas limited to the aqueductal region of the tectum of the mesencephalon. The characteristic presentation of hydrocephalus without brain-stem signs is described. Careful radiological examination, including computerized axial tomography, failed to reveal any evidence of tumor. The diagnosis was established at postmortem examination. Literature review yielded 12 previous cases of similar presentation.
Henry G. Schwartz
Edited by Robert A. Ratcheson
✓ In his final address to the Society of Neurological Surgeons, Henry G. Schwartz, M.D., shared his thoughts on mentoring and recalled specific mentors who contributed to his professional life.
Bernard S. Patrick, Robert R. Smith and Terry O. Bailey
✓The authors report a case in which spontaneous extravasation of the contents of a supracellular cyst produced aseptic meningitis.
John P. Kapp and Robert R. Smith
✓ The authors review the literature concerning spontaneous resolution of occlusive lesions involving the carotid artery. They add four cases illustrating three pathological vascular processes that may resolve spontaneously, namely, arterial dissection, atheromatous lesions at the carotid bifurcation, and an arteriopathy involving the intracranial vessels which is poorly understood at this time.