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Martin H. Weiss

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Martin H. Weiss

✓ The author provides a brief history of the genesis of organized neurosurgery and, in particular, the formation and evolution of the American Association of Neurological Surgeons. The legacy of neurosurgery is noted and the author discusses the present and future practice of neurosurgery.

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Martin H. Weiss and Frank E. Nulsen

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Martin H. Weiss and John A. Jane

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Martin H. Weiss and Uros Roessmann

✓ Hydrocephalic animals were given an intraventricular infusion of radioactive colloidal gold and then sacrificed up to 7 weeks after infusion. Histological evaluation revealed progression from a marked hemorrhagic necrosis of choroid plexus vessels and stroma to eventual replacement by fibrous connective tissue, sclerosis, and fibrinous degeneration of stromal vessels. Particulate colloid was found engulfed in perivascular spaces in the subependymal periventricular tissues, but there was no evidence of vascular damage, gliosis, or demyelination. These findings may play a role in decreasing cerebrospinal fluid production.

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Milton D. Heifetz and Martin Weiss

✓ A technique is described which uses standard strain-gauge technology to detect skull expansion associated with increased intracranial pressure.

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Felipe C. Albuquerque, David R. Hinton, and Martin H. Weiss

✓ The authors report the case of a 48-year-old woman who presented with a nonprolactin-secreting adenoma and a preoperative prolactin level of 662 ng/ml. The patient's neoplasm subsequently enlarged despite normalization of her prolactin level with dopamine agonist therapy. Hyperprolactinemia, with levels of prolactin as high as 150 ng/ml, is commonly associated with sellar tumors and is attributed to disruption of the normal delivery of dopamine to the adenohypophysis. The prolactin level found in this patient represents the highest level attributed to the stalk-section effect reported in the literature and underscores the need for repeated radiographic assessment of patients who are undergoing treatment with bromocriptine and have prolactin levels in the 25 to 1000 ng/ml range.

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Martin H. Weiss, Harold F. Young, and Dee E. McFarland

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Robert M. Weiss, Lawrence Sweeney, and Martin Dreyfuss

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Sixth nerve schwannomas

Report of two cases

Howard Tung, Thomas Chen, and Martin H. Weiss

✓ Two cases of sixth cranial nerve schwannoma are presented with a review of four other cases from the literature. The clinical spectrum, neuroradiological findings, and surgical outcome of the six cases are discussed. There are two distinct clinical presentations for sixth cranial nerve schwannomas. Type I sixth nerve schwannomas present with sixth nerve palsy and diplopia and arise from the cavernous sinus. In contrast, type II sixth nerve schwannomas have a more severe presentation with obstructive hydrocephalus, raised intracranial pressure, sixth nerve palsy, and diplopia. This type arises along the course of the sixth cranial nerve in the prepontine area. Cavernous sinus involvement in either type may preclude total surgical excision and indicate an increased possibility for recurrence.