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Walavan Sivakumar, Michael Jensen, Julie Martinez, Michael Tanana, Nancy Duncan, Robert Hoesch, Jay K. Riva-Cambrin, Craig Kilburg, Safdar Ansari and Paul A. House

In Brief

The authors designed a randomized, double-blinded, placebo-controlled trial to evaluate intravenous acetaminophen as a scheduled adjunct with our standardized craniotomy pain control regimen. No statistically significant effect was found in narcotic consumption at 24 or 48 hours after surgery. At 24 but not 48 hours, patients treated with intravenous acetaminophen did report significantly lower pain scores than patients given the placebo. These data provide only modest support for using intravenous acetaminophen to improve postoperative craniotomy pain.

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Oral Presentations

2010 AANS Annual Meeting Philadelphia, Pennsylvania May 1–5, 2010