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  • By Author: Link, Michael J. x
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Brian A. Neff, Matthew L. Carlson, Megan M. O'Byrne, Jamie J. Van Gompel, Colin L. W. Driscoll and Michael J. Link

approach; tumor resection completeness; inadvertent intraoperative fifth nerve injury (partial or complete transection); presence of a compressive vessel on the trigeminal nerve; concurrent microvascular decompression with tumor removal; postoperative neuralgia, numbness, or paresthesia outcome; time until symptom improvement; tumor size; cystic nature of tumor; pain medication reduction; SRS treatment details including treatment volume, central and marginal dose, number of isocenters, surgical and radiation complications (e.g., facial paralysis); and duration of follow

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Matthew L. Carlson, Jeffrey T. Jacob, Bruce E. Pollock, Brian A. Neff, Nicole M. Tombers, Colin L. W. Driscoll and Michael J. Link

; tumor characteristics (laterality, location [extent of internal auditory canal and CPA involvement], size, volume, macrocystic features, distance to fundus, and brainstem contact); NF2 status; history of prior tumor treatment; and basic demographic information (age and sex). Pretreatment tumor size, location, and hearing capacity were reported according to the 1995 AAO-HNS guidelines. 4 Patients with serviceable hearing (AAO-HNS Class A or B) prior to SRS who received low-dose (12- to 13-Gy marginal dose) SRS between 1997 and 2002 were identified. Preliminary

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Neil S. Patel, Matthew L. Carlson, Bruce E. Pollock, Colin L. W. Driscoll, Brian A. Neff, Robert L. Foote, Christine M. Lohse and Michael J. Link

. Unique to this series is serial measurement of tumor size using 3D tumor segmentation to provide an accurate assessment of tumor progression that avoids error introduced by volume approximation formulae or linear measurements. Three-dimensional volumetric segmentation is particularly advantageous for JP, where the amorphous and infiltrative growth pattern renders other methods imprecise. Methods Data Collection Following Mayo Clinic IRB approval, a retrospective review of paper and electronic medical records for all patients with a diagnosis of JP treated with GKRS was

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Neil S. Patel, Matthew L. Carlson, Bruce E. Pollock, Colin L. W. Driscoll, Brian A. Neff, Robert L. Foote, Christine M. Lohse and Michael J. Link

. Unique to this series is serial measurement of tumor size using 3D tumor segmentation to provide an accurate assessment of tumor progression that avoids error introduced by volume approximation formulae or linear measurements. Three-dimensional volumetric segmentation is particularly advantageous for JP, where the amorphous and infiltrative growth pattern renders other methods imprecise. Methods Data Collection Following Mayo Clinic IRB approval, a retrospective review of paper and electronic medical records for all patients with a diagnosis of JP treated with GKRS was

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William R. Schmitt, Jasper R. Daube, Matthew L. Carlson, Jayawant N. Mandrekar, Charles W. Beatty, Brian A. Neff, Colin L. Driscoll and Michael J. Link

study . Otolaryngol Head Neck Surg 89 : 767 – 775 , 1981 16 Isaacson B , Kileny PR , El-Kashlan H , Gadre AK : Intraoperative monitoring and facial nerve outcomes after vestibular schwannoma resection . Otol Neurotol 24 : 812 – 817 , 2003 17 Kartush JM , Niparko JK , Bledsoe SC , Graham MD , Kemink JL : Intraoperative facial nerve monitoring: a comparison of stimulating electrodes . Laryngoscope 95 : 1536 – 1540 , 1985 18 Kirkpatrick PJ , Tierney P , Gleeson MJ , Strong AJ : Acoustic tumour volume and the

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Avital Perry, Christopher S. Graffeo, Lucas P. Carlstrom, Aditya Raghunathan, Colin L. W. Driscoll, Brian A. Neff, Matthew L. Carlson, Ian F. Parney, Michael J. Link and Jamie J. Van Gompel

c9fbf 14 de Vries M , Hogendoorn PC , Briaire-de Bruyn I , Malessy MJ , van der Mey AG : Intratumoral hemorrhage, vessel density, and the inflammatory reaction contribute to volume increase of sporadic vestibular schwannomas . Virchows Arch 460 : 629 – 636 , 2012 10.1007/s00428-012-1236-9 15 Edin S , Wikberg ML , Dahlin AM , Rutegård J , Öberg Å , Oldenborg PA , : The distribution of macrophages with a M1 or M2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer . PLoS One 7 : e47045

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Matthew L. Carlson, Oystein Vesterli Tveiten, Colin L. Driscoll, Frederik K. Goplen, Brian A. Neff, Bruce E. Pollock, Nicole M. Tombers, Marina L. Castner, Monica K. Finnkirk, Erling Myrseth, Paal-Henning Pedersen, Morten Lund-Johansen and Michael J. Link

following treatment were relatively small. These data support the notion that the diagnosis of VS imparts a significant reduction on HRQOL, while long-term differences between treatment strategies are generally less significant by comparison. We believe that further meaningful gains in HRQOL will require a redirection of efforts. While facial nerve function and tumor control are important, results from large-volume centers have largely plateaued within the last several decades. Moving forward, improvements in patient counseling regarding realistic long-term expectations