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Stereotactic radiosurgery for trigeminal neuralgia: a systematic review

International Stereotactic Radiosurgery Society practice guidelines

Constantin Tuleasca, Jean Régis, Arjun Sahgal, Antonio De Salles, Motohiro Hayashi, Lijun Ma, Roberto Martínez-Álvarez, Ian Paddick, Samuel Ryu, Ben J. Slotman and Marc Levivier

myelination (Schwann cells) transitions to central myelination (oligodendrocytes). The REZ is not fixed, and its location can vary from 0 to 3 mm from the nerve’s exit from the brainstem and is impossible to visualize on in vivo imaging. Some authors make the choice of an anterior versus a posterior target based on the idea that the nerve is more radiosensitive at the REZ than at the anterior part. Target Placement and Related Complications: Indirect Evidence From Dose-Volume Histograms Only 1 study documented dose-volume effects on the brainstem (dose-volume histogram [DVH

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Stereotactic body radiotherapy for de novo spinal metastases: systematic review

International Stereotactic Radiosurgery Society practice guidelines

Zain A. Husain, Arjun Sahgal, Antonio De Salles, Melissa Funaro, Janis Glover, Motohiro Hayashi, Masahiro Hiraoka, Marc Levivier, Lijun Ma, Roberto Martínez-Alvarez, J. Ian Paddick, Jean Régis, Ben J. Slotman and Samuel Ryu

fraction was delivered using a simultaneous integrated boost technique (24 Gy to gross tumor volume [GTV] in 1 patient and 18 Gy to clinical target volume [CTV] in 1 patient). Although none of the patients had undergone radiation previously, some patients had undergone previous surgical procedures; thus, inclusion was limited to 47 lesions in patients without previous surgery. The median follow-up duration for the entire group was 20 months. The median survival time for the entire group was 30 months, and survival times were similar in postoperative and de novo patients

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Stereotactic radiosurgery for tremor: systematic review

International Stereotactic Radiosurgery Society practice guidelines

Nuria E. Martínez-Moreno, Arjun Sahgal, Antonio De Salles, Motohiro Hayashi, Marc Levivier, Lijun Ma, Ian Paddick, Jean Régis, Sam Ryu, Ben J. Slotman and Roberto Martínez-Álvarez

to the volume of brain parenchyma receiving a given dose. Several indices are used to estimate that volume, e.g., the gradient index. 62 , 63 , 76 Matrix size also appears to have an influence. Larger matrices may result in longer procedure times, longer exposure times, and higher total doses. 65 Using a single smaller collimator helps minimize the dose to peripheral tissue. Lindquist et al. 42 reported 2 patients who were treated with doses of 180 and 200 Gy, using an 8- and 4-mm collimator, respectively. The lower dose yielded greater response but also more

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Reirradiation spine stereotactic body radiation therapy for spinal metastases: systematic review

International Stereotactic Radiosurgery Society practice guidelines

Sten Myrehaug, Arjun Sahgal, Motohiro Hayashi, Marc Levivier, Lijun Ma, Roberto Martinez, Ian Paddick, Jean Régis, Samuel Ryu, Ben Slotman and Antonio De Salles

within months of the first treatment course. The need for reirradiation is expected only to increase as more effective surgical, radiation, and systemic therapies continue to result in longer lengths of patient survival. Management of progressive spinal disease within a previously irradiated volume has been a major challenge given the proximity of several critical structures, in particular, the spinal cord. Respecting the cumulative tolerance of the spinal cord has historically led to conservative practice among radiation oncologists and retreatment with lower