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Darryl Lau, Andrew K. Chan, Vedat Deverin and Christopher P. Ames

A dult spinal deformity (ASD) can result in sagittal and/or coronal imbalance, which is generally the result of asymmetrical degeneration of vertebral bodies, intervertebral discs, and facet joints. 9 This progressive degenerative process can be hastened in the setting of concurrent spinal disease (chronic fractures and remote infection) or in patients with a history of prior spinal surgery with or without spinal instrumentation. Patients with ASD typically present with debilitating axial back and neck pain, neurological deficits, and functional impairment

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Darryl Lau, Vedat Deviren and Christopher P. Ames

A dult spinal deformity (ASD) arises from multiple etiologies, but most commonly it arises from arthritic spondylosis and iatrogenic causes that lead to asymmetrical degeneration of discs, facet joints, and other spinal elements. Imbalance and spinal misalignment are strongly correlated with disability and pain outcomes—greater imbalance results in greater functional disability. 14 , 22 , 39 Fortunately, the surgical correction and reestablishment of age-appropriate global spinal alignment and spinopelvic parameters have been demonstrated to significantly

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Darryl Lau, Dean Chou and Praveen V. Mummaneni

degrees indicated straightening of the spine and no curvature. The need for supplemental PSF was recorded. The primary outcomes of interest were postoperative sagittal Cobb angle, adjacent-segment disease (ASD), neck pain VAS score, and Nurick score. ASD was defined as new disease affecting the level inferior and/or superior to the operated levels that required surgery. Secondary outcomes of interest included estimated blood loss (EBL), dysphagia, length of stay, perioperative complications, perioperative mortality, and pseudarthrosis rate. The EBL was recorded in

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Cecilia L. Dalle Ore, Christopher P. Ames, Vedat Deviren and Darryl Lau

study compares perioperative and long-term outcomes of RA adult spinal deformity (ASD) patients to a matched cohort of non-RA ASD patients based on demographics, comorbidities, surgical approach, and spinal construct similarity. Methods This study was formally approved by the Committee of Human Research at the University of California, San Francisco. Patient Cohort Patients were identified via a comprehensive retrospective review of the electronic medical record. This study included all adult patients (over age 18 years at time of surgery) who underwent a posterior

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Darryl Lau, Joseph A. Osorio, Vedat Deviren and Christopher P. Ames

A dult spinal deformity (ASD) arises from multiple etiologies, but most commonly from arthritic spondylosis leading to asymmetrical degeneration of discs, facet joints, and other spinal elements. 13 This degenerative process can be hastened by iatrogenic factors (such as prior spine surgery) that result in instability, which further leads to instrumentation failure and junctional kyphosis/failure. ASD can be asymptomatic but is most often progressive, leading to severe axial back pain and neurological deficits in the setting of compression of neural elements

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Darryl Lau, Cecilia L. Dalle Ore, Patrick Reid, Michael M. Safaee, Vedat Deviren, Justin S. Smith, Christopher I. Shaffrey and Christopher P. Ames

surgical interventions. Pediatric cases often involve scoliosis, coronal imbalance, and the thoracic region, whereas adult spinal deformity (ASD) cases more often involve sagittal imbalance, spinopelvic mismatch, and the lumbar spine. Thus, the results from pediatric studies may not be directly applicable to an ASD population. MEP use is best understood in spine surgery as a measure for spinal cord monitoring, and the true utility of using transcranial MEPs when operating in the lumbar spine (a region of thecal sac and nerve roots without spinal cord) remains

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adjacent segment disease (ASD) in the cervical spine. Methods: 888 patients received ACDFs for symptomatic degenerative disease of the cervical spine over the past 22 years at our institution. Of these, 108 patients received repeat ACDF surgeries due to symptomatic ASD. 77 received revision surgeries anteriorly, and 31 received posterior surgeries. Pre, intra, peri, and post-operative data were collected via clinical notes and patient interviews. Patients were followed up for an average of 111.8±76.5 months after the first ACDF. Results: In general, patients

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between the two forms of treatment emerge. Neurosurg Focus Neurosurgical Focus FOC 1092-0684 American Association of Neurological Surgeons 2015.3.FOC-DSPNABSTRACTS 103. A Prospective, Multi-Center Assessment of the Best Versus Worst Clinical Outcomes for Adult Spinal Deformity (ASD) Surgery Justin S. Smith , MD PhD , Christopher I. Shaffrey , MD FACS , Virginie Lafage , PhD , Frank Schwab , MD, PhD , Themistocles Protopsaltis , MD , Eric Klineberg , MD , Munish

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remains stable comparing 3 and 12-month results. Neurosurg Focus Neurosurgical Focus FOC 1092-0684 American Association of Neurological Surgeons 2014.3.FOC-DSPNABSTRACTS Abstract Outcomes Award 103. Two Year Prospective, Multicenter Analysis of Consecutive Adult Spinal Deformity (ASD) Patients Demonstrates Higher Fusion Grade, Lower Implant Failures and Greater Improvement in SRS-22r Scores for Patients Treated with Recombinant Human Bone Morpho Kai-Ming G. Fu , MD PhD , Eric Klineberg , MD , Shay

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Association of Neurological Surgeons. You may not sell, republish, or systematically distribute any published materials without written permission from JNSPG. 2015 Introduction The neurologic complication rate following complex adult spinal deformity surgery (ASD) has not been ascertained in any prospective, multicenter, observational study. Here, we compare preoperative lower extremity motor scores (LEMS) to 6 month postoperative scores. Methods 276 complex ASD patients from 15 sites worldwide were enrolled in this prospective, multicenter