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regional EMS providers. Data from 2008 through 2012 were analyzed before and after NOTS formation in 2010. Multivariate regression analysis (RA) was performed to evaluate independent predictors of survival. Results 11,220 patients were identified with TBI in the NOTS database; 4, 507 (40%) before NOTS and 6, 713 (60%) after NOTS. Admissions to the regional level 1 center post-NOTS increased from 36% to 46% (p <0.0001). Injury severity scores and Abbreviated Injury Scores (AIS) were similar between periods. The mortality rate decreased from 6.2% to 4.9% (p=0

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country-wide. The overall incidence of trauma associated pediatric coma decreased in 2012, perhaps reflecting the success of awareness and prevention efforts. However mortality rates remain unchanged from 1997 – 2012, indicating a clear role for future efforts to better describe, characterize, and treat the underlying pathology. J Neurosurg Journal of Neurosurgery JNS 0022-3085 1933-0693 American Association of Neurological Surgeons 2015.8.JNS.AANS2015ABSTRACTS Abstract 502. Effect of Antiplatelet Therapy and Platelet Function

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, Oswestry Disability Index (ODI), and EQ-5D scores, were obtained both preand post-operatively. Results: The median survival was 7.7 months. The 30-day and 12-month mortality rates were 9% and 62%, respectively. Six weeks post-operatively, ambulatory status (p = 0.02) and bladder control (p = 0.03) were significantly improved. Overall, 67.5% of ASIA B, C, or D patients gained at least 1 grade after surgery, 25% remained stable, and 7.5% deteriorated. ODI, EQ-5D, BPI scores were significantly improved at each follow-up (p ≤ 0.01). SF-36 scores were generally higher

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-hospital mortality, discharge disposition, and of a poor outcome (death, tracheostomy or gastrostomy placement, or discharge to institutional care). Covariates included patient age, sex, comorbidities, NIS-SAH severity scale, and hospital characteristics. Thereafter, subgroup analyses evaluated patients separately who were treated microsurgically or endovascularly. Results: A total of 18,281 patients were included. The in-hospital mortality rate was 13.4% during the entire study period: 15.3% in 2002 and 10.7% in 2011. In multivariable logistic regression, more recent year