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Jason P. Sheehan, Ming-Hsi Sun, Douglas Kondziolka, John Flickinger and L. Dade Lunsford

. In that same series, a surgical mortality rate of 1.3% was also noted. Surgical outcomes were best in patients with solitary, surgical accessible tumors and in patients in whom there was no active systemic disease. 25, 26, 36 In the present radiosurgical series, no treatment-related deaths occurred. The number of metastases (as many as 12 tumors) did not correlate with patient survival. Radiosurgery can be used to treat multiple widely separated brain metastases in a single session. In a randomized trial in which fractionated radiotherapy and resection (median

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Jason P. Sheehan, Ming-Hsi Sun, Douglas Kondziolka, John Flickinger and L. Dade Lunsford

in which investigators had compared the combination of fractionated radiation therapy and resection (median survival 5.6 months) with radiation therapy alone (median survival 6.3 months), no statistically significant difference in survival was demonstrated. 32 Note that the median length of survival in surgically treated patients with multiple tumors was worse at 6 months. 8 In two series of patients with brain metastasis of renal cell carcinoma who had undergone surgery, operative mortality rates varied between 9 and 10% and postoperative complication rates were

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Jason Sheehan, Douglas Kondziolka, John Flickinger and L. Dade Lunsford

and radiosurgery. It is unusual for patients to die of residual or recurrent tumor unless there is significant intracranial extension. 56 As such, regardless of the treatment modality chosen, significant emphasis should be placed not just on decreasing mortality rates but also on decreasing the morbidity associated with glomus jugulare tumors. Complete resection of these tumors is best accomplished by a skull base surgical team composed of a neurosurgeon, otolaryngologist, and someone experienced in free vascularized flaps. 23 Microsurgical resection of these

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Jason Sheehan, Douglas Kondziolka, John Flickinger and L. Dade Lunsford

mortality rate of 1.3% was noted in one large series. 59 These large surgical series generally focus on patients with non—small cell lung carcinoma metastases. An occasional case of a surgically treated patient with small cell lung cancer metastatic to the brain is reported in the literature. 1 Resection is generally reserved for selected small cell lung cancer patients who have well-controlled extracranial disease and a solitary brain metastasis. 1 In larger series of patients with brain metastases of various origins, surgical outcomes were best in patients with

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country-wide. The overall incidence of trauma associated pediatric coma decreased in 2012, perhaps reflecting the success of awareness and prevention efforts. However mortality rates remain unchanged from 1997 – 2012, indicating a clear role for future efforts to better describe, characterize, and treat the underlying pathology. J Neurosurg Journal of Neurosurgery JNS 0022-3085 1933-0693 American Association of Neurological Surgeons 2015.8.JNS.AANS2015ABSTRACTS Abstract 502. Effect of Antiplatelet Therapy and Platelet Function

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, Oswestry Disability Index (ODI), and EQ-5D scores, were obtained both preand post-operatively. Results: The median survival was 7.7 months. The 30-day and 12-month mortality rates were 9% and 62%, respectively. Six weeks post-operatively, ambulatory status (p = 0.02) and bladder control (p = 0.03) were significantly improved. Overall, 67.5% of ASIA B, C, or D patients gained at least 1 grade after surgery, 25% remained stable, and 7.5% deteriorated. ODI, EQ-5D, BPI scores were significantly improved at each follow-up (p ≤ 0.01). SF-36 scores were generally higher

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-hospital mortality, discharge disposition, and of a poor outcome (death, tracheostomy or gastrostomy placement, or discharge to institutional care). Covariates included patient age, sex, comorbidities, NIS-SAH severity scale, and hospital characteristics. Thereafter, subgroup analyses evaluated patients separately who were treated microsurgically or endovascularly. Results: A total of 18,281 patients were included. The in-hospital mortality rate was 13.4% during the entire study period: 15.3% in 2002 and 10.7% in 2011. In multivariable logistic regression, more recent year