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, with >90% of cells confirmed to have EC identity on flow cytometry (CD45-CD31+). These cells were also significantly enriched for EC-related genes such as Cdh5, Icam2, Nos3 and Pecam1. Microarray results will provide a list of genes that are significantly upregulated or downregulated in BECs after SAH, requiring further validation studies. Conclusion: BBB disruption is greater at 24h than at 48h in an experimental SAH model. This study is the first to provide whole genome expression profiling of freshly-isolated BECs derived from an SAH animal model. Thereby

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spinal fusion, which has became the standard of care. With reducing trend of autograft, BMP and newer bone grafts able to reduce infection rate and improve bony fusion. J Neurosurg Journal of Neurosurgery JNS 0022-3085 1933-0693 American Association of Neurological Surgeons 10.3171/2017.4.JNS.AANS2017abstracts 2017.4.JNS.AANS2017ABSTRACTS Oral Presentations 508. Brain repair and neural network remodeling by hematopoietic growth factors in subacute phase of traumatic brain injury in animal model Gentian Toshkezi