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Mildred S. Yang, Douglas S. DeWitt, Donald P. Becker and Ronald L. Hayes

brain electrical activity by electroencephalography (EEG). The PaCO 2 , PaO 2 , and pH were measured using a blood gas analyzer, ‡ and animals were considered stable when these values remained within normal limits 11 over a 30-minute period without manipulation of the ventilatory rate or volume, or administration of bicarbonate. An injury pulse of 1.9 to 2.2 atm was delivered to the brains of six animals. One hour after the injury, PaCO 2 , PaO 2 , and arterial pH were again measured, and 1 cc of arterial blood was drawn for analysis of blood glucose. At this time

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Douglas S. DeWitt, Larry W. Jenkins, Enoch P. Wei, Harry Lutz, Donald P. Becker and Hermes A. Kontos

mechanically ventilated on room air supplemented with O 2 as needed. A cannula (PE 90) was placed in the right femoral artery to monitor arterial blood pressure and withdraw samples for measurement of PaCO 2 , PaO 2 , and pH. These parameters were maintained within normal limits for cats 21 by adjustment of the ventilatory rate and volume. Body temperature was measured periodically and regulated by an infrared heat source. Cannulae (PE 90) were also placed in the right brachial and left femoral arteries for withdrawal of reference arterial samples, and a PE 160 cannula was