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Stephen J. Hentschel, Remi Nader, Dima Suki, Amer Dastgir, David L. Callender and Franco DeMonte

series reporting survival and complications of craniofacial resections * Authors & Year No. of Patients Mean Age (yrs) No. of Patients w/ Malignant Tumors (%) Mortality Rate (%) Morbidity Rate (%) Survival Rate (%) Janecka, et al., 1994 183 44 64 2 33, 20 (L), 12 (S) 67 (O) Clayman, et al., 1995 39 61 100 0 41, 23 (L), 18 (S) 55 (5-yr DS) McCutcheon, et al., 1996 76 49 95 1 36, 36 (L), NA (S) 63 (2-yr O) Dias, et al., 1997 104 62 94 7.6 49, 45 (L), 10 (S) 61

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Giacomo G. Vecil, Dima Suki, Marcos V. C. Maldaun, Frederick F. Lang and Raymond SaWaya

.054 * Referent group to which other groups are compared. † Treatment of nonindex lesions occurred either before, after, or at the same time as treatment of index lesions. The cause of death was neurological in 15% of patients, systemic in 43%, both neurological and systemic in 34%, and undetermined in 8%. The surgical mortality rate was 3%, with two patients dying within 30 days after the surgical procedure. The causes of death in these two patients were systemic: one died of pneumonia and the other died of acute respiratory distress syndrome. Both patients

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Paul J. Holman, Dima Suki, Ian McCutcheon, Jean-Paul Wolinsky, Laurence D. Rhines and Ziya L. Gokaslan

complications included ileus (10 patients), deep venous thrombosis (four patients), atrial fibrillation (two patients), minor gastrointestinal bleeding (two cases), durotomy with primary repair (two cases), and superficial wound infection, pleural effusion, mild pancreatitis, urinary tract infection, atelectasis, altered mental status, and an oral pressure ulcer related to the endotracheal tube (one case each). The overall 30-day mortality rate was 5% (seven of 139 cases). Early complications occurred in 17 patients (31%)in Group 1, six patients (15 and 26%, respectively

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Ganesh Rao, Dima Suki, Indro Chakrabarti, Iman Feiz-Erfan, Milan G. Mody, Ian E. McCutcheon, Ziya Gokaslan, Shreyaskumar Patel and Laurence D. Rhines

mortality rate was 0. TABLE 1 Distribution of sarcoma histological types among the 80 patients with primary or metastatic sarcomas of the spine * Sarcoma Group Histological Type Primary Metastatic chondrosarcoma 16 5 leiomyosarcoma 1 21 osteosarcoma 4 6 liposarcoma 1 8 rhabdomyosarcoma 0 1 synovial cell sarcoma 3 1 unclassified 3 6 other 1 3 * Data in columns represent numbers of patients. Some neoplasms were resected more than once. Functional Outcomes Of the 110

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Mark Dannenbaum, Bradley C. Lega, Dima Suki, Richard L. Harper and Daniel Yoshor

James ML , Husain AM : Brainstem auditory evoked potential monitoring: when is change in wave V significant? . Neurology 65 : 1551 – 1555 , 2005 15 Kalkanis SN , Eskandar EN , Carter BS , Barker FG : Microvascular decompression surgery in the United States, 1996 to 2000: mortality rates, morbidity rates, and the effects of hospital and surgeon volumes . Neurosurgery 52 : 1251 – 1261 , 2003 16 Lovely TJ , Getch CC , Jannetta PJ : Delayed facial weakness after microvascular decompression of cranial nerve VII . Surg Neurol 50

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Benjamin D. Fox, Akash Patel, Dima Suki and Ganesh Rao

/cartilage or soft-tissue–derived sarcoma, and control of systemic disease. Complications The 30-day mortality rate was 4.2% (2 of 47 patients with adequate follow-up). Neither patient died of direct or secondary neurological complications of the craniotomy and resection of the tumor or of neurological progression of the tumor. One of the patients died prior to discharge from the hospital following surgery of uncontrollable bilateral spontaneous hemorrhage of his diffuse lung metastases. The second patient was discharged postcraniotomy with an improved KPS score and

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Brian J. Williams, Dima Suki, Benjamin D. Fox, Christopher E. Pelloski, Marcos V. C. Maldaun, Raymond E. Sawaya, Frederick F. Lang and Ganesh Rao

direct consequences of SRS if they were clearly related to treatment (for example, cerebral hemorrhage, hydrocephalus, and headache). Data on other adverse outcomes were also collected, including deep venous thrombosis, steroid dependency, Cushing syndrome, and nausea, although these outcomes were not considered complications of SRS. Steroid dependency was defined as the continuous use of steroids at 3 months, 6 months, or 1 year after treatment and was not considered a complication. The mortality rate 30 days post-SRS was recorded but not included as a direct

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Wael Hassaneen, Dima Suki, Abhijit L. Salaskar, David M. Wildrick, Frederick F. Lang, Gregory N. Fuller and Raymond Sawaya

occurred in 3 patients and were controlled by antiseizure medications. One patient experienced a venous infarct after undergoing tumor resection via the transcallosal approach. This infarct may have resulted from cauterization of one of the draining veins. There were 3 cases (10%) of systemic complications, all of which were major. The median postoperative KPS score was 80. In 19 cases (66%), the postoperative KPS score was the same as it was preoperatively; the score was worse in 9 patients (31%); and it improved in 1 (3%). The surgery-related mortality rate was 7%. The

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Oral Presentations

2010 AANS Annual Meeting Philadelphia, Pennsylvania May 1–5, 2010

tumor for which outcomes were reported; and 3) patient variables that permitted statistical aggregation. Exclusion criteria were: 1) all Rathke's pouch tumors; 2) other childhood tumors; and 3) inadequate mortality follow-up data. IRB approval was obtained from UCSF. Results: A total of 8058 patients met the inclusion criteria and had quantifiable outcome data treated for craniopharyngioma. The recurrence rate was 13% (1053 patients), with a median follow-up length of 48 months (range 1–360 months) and mortality rate of 2% (186 patients). Radiotherapy alone had

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Roukoz Chamoun, Dima Suki, Shankar P. Gopinath, J. Clay Goodman and Claudia Robertson

inserted. Invasive monitoring devices were removed when ICP was well controlled (without requiring mannitol, CSF drainage, or heavy sedation) and/or the patient showed significant improvement in neurological status. Clinical and radiological characteristics are summarized in Tables 1 and 2 . At 6 months of follow-up, the mortality rate was 23.6%. Among those who survived, 46 patients had a good functional outcome (GOS Score 4 or 5). Patient outcomes at 6 months of follow-up are summarized in Table 3 . TABLE 1: Summary of clinical characteristics in 165