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Ronald F. Young and Kent M. Perryman

abolished by tractotomy. 9, 27 These more recent experiments appear to question the role of a caudal to rostral facilitatory influence among the trigeminal brain-stem relay nuclei in dental pain perception, although they do not shed light onto the potential role of such interactions in cutaneous facial nociception. The present experiments were undertaken in an attempt to correlate behavioral and electrophysiological observations in monkeys following chronic trigeminal tractotomy, in order to better assess the potential contribution of modulation of rostral trigeminal

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Ronald F. Young, Terrence D. Oleson and Kent M. Perryman

The first proposal, which has received recent neurophysiological support, 37 stated that the trigeminal nucleus caudalis was the exclusive termination point of primary afferent fibers related to facial nociception. 10, 44 Such afferents were assumed to synapse with second-order neurons, which relayed nociceptive-related information centrally to the thalamus and other higher centers for cognitive processing. Anatomical 46 and physiological 14, 20, 41, 42, 58 evidence of internuclear interaction within the various divisions of the spinal trigeminal brain