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Shunji Nishio, Takatoshi Tashima, Iwao Takeshita and Masashi Fukui

on light microscopy resembled oligodendroglioma and which showed the ultrastructural characteristics of neuronal neoplasms. They coined the term “central neurocytoma” for these tumors. This neoplasm has not become a distinct clinical and pathological entity because of its rare occurrence and its rather recent recognition. In this paper, the cases of six patients with so-called “intraventricular oligodendroglioma” are reviewed, and the ultrastructural resemblance of these tumors to central neurocytoma is confirmed. Clinical Material and Methods Six patients

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Hypothalamic hamartoma

Report of two cases

Shunji Nishio, Shigeru Fujiwara, Yasutaka Aiko, Iwao Takeshita and Masashi Fukui

neuronal populations based on neuropeptide patterns suggests that some neurons in our cases have functional similarities to the hypothalamic neurons, and may also indicate the hamartomatous nature of our lesion. Some neuronal neoplasms, including ganglioglioma, have also been shown to have neuropeptides, which are characteristic of the hypothalamus. 19 In addition, some neuronal elements in our hamartoma showed positive immunohistochemical reaction for a 210-kD neurofilament protein, a positivity found only in some processes of Purkinje cells in the normal cerebellum