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  • Journal of Neurosurgery: Spine x
  • By Author: Liu, James K. x
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Osamah J. Choudhry, Lana D. Christiano, Rahul Singh, Barbara M. Golden and James K. Liu

. Spine surgeons should be aware of this complication, and care should be taken not to overpack the interbody cage. The management of inflammatory cyst formation has not been clearly defined in the literature. Options include a conservative approach of medical therapy, CT-guided cyst aspiration to decompress the cyst, or surgical reexploration to excise or drain the cyst to decompress the nerve root. Observation may be feasible if the patient is asymptomatic or adequately controlled on medical therapy. Computed tomography–guided aspiration of cyst fluid offers a

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Cervical spinal cord delivery of a rabies G protein pseudotyped lentiviral vector in the SOD-1 transgenic mouse

Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2004

Kiana Tanase, Qingshan Teng, Ajit A. Krishnaney, James K. Liu, Mary E. Garrity-Moses and Nicholas M. Boulis

pathological characteristics of ALS are reproduced in transgenic mice that overexpress a human mutant SOD-1 (G93A), which has a dominant gain-of-function effect. 16 Motor neurons degenerate at a rapid pace in these transgenic animals, ultimately resulting in death, 2, 8, 22 and the mice serve as a reliable model for testing potential therapies for ALS. For a number of years it has been recognized that neurotrophic factors may play a role in enhancing neuronal survival and axonal regeneration 26, 31 after spinal trauma and in neurodegenerative diseases. 6, 7, 17