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Justin S. Smith, Eric Klineberg, Virginie Lafage, Christopher I. Shaffrey, Frank Schwab, Renaud Lafage, Richard Hostin, Gregory M. Mundis Jr., Thomas J. Errico, Han Jo Kim, Themistocles S. Protopsaltis, D. Kojo Hamilton, Justin K. Scheer, Alex Soroceanu, Michael P. Kelly, Breton Line, Munish Gupta, Vedat Deviren, Robert Hart, Douglas C. Burton, Shay Bess, Christopher P. Ames and the International Spine Study Group

for 13% of all major complications, and the most common operative complication was anemia/excessive blood loss. Multiple studies have demonstrated the potential effectiveness of intraoperative antifibrinolytic therapy in significantly reducing blood loss (A. Soroceanu et al., unpublished data). 9 , 36 , 65 In addition, a recently published application of rotational thromboelastometry-guided blood product management to major spine procedures suggests that this technology may aid in reducing blood loss, blood product use, and cost. 31 Infections accounted for 9% of