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Peter D. Le Roux, David W. Newell, Arthur M. Lam, M. Sean Grady and H. Richard Winn

NM , et al : The effect of changes in cerebral perfusion pressure upon middle cerebral artery blood flow velocity and jugular bulb venous oxygen saturation after severe brain injury. J Neurosurg 77 : 55 – 61 , 1992 Chan KH, Miller JD, Dearden NM, et al: The effect of changes in cerebral perfusion pressure upon middle cerebral artery blood flow velocity and jugular bulb venous oxygen saturation after severe brain injury. J Neurosurg 77: 55–61, 1992 9. Cold GE , Jensen T : Cerebral autoregulation in unconscious

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J. Paul Elliott, David W. Newell, Derek J. Lam, Joseph M. Eskridge, Colleen M. Douville, Peter D. Le Roux, David H. Lewis, Marc R. Mayberg, M. Sean Grady and H. Richard Winn

) * GOS = Glasgow Outcome Scale; SEM = standard error of the mean. † Favorable = good or moderately disabled; unfavorable = severely disabled, vegetative, or dead. Velocity Measurement by Means of TCD After Treatment of Vasospasm Balloon Angioplasty In 101 vessel segments in 39 patients treated with balloon angioplasty, the mean combined TCD-measured blood flow velocity in the distal ICA and proximal MCA increased from a baseline of 95 ± 12 to 166 ± 9 cm/second just before treatment. This decreased significantly to 92 ± 4 cm/second following

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al : Effect of age on cerebral blood flow velocity and incidence of vasospasm after aneurysmal subarachnoid hemorrhage. Stroke 32 : 2005 – 2011 , 2001 Torbey MT, Hauser TK, Bhardwaj A, Williams MA, Ulatowski JA, Mirski MA, et al: Effect of age on cerebral blood flow velocity and incidence of vasospasm after aneurysmal subarachnoid hemorrhage. Stroke 32: 2005–2011, 2001 Neurosurgical Forum: Letters to the Editor Response Peter D. Le Roux , M.D. Penn Neurological Institute Philadelphia

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Michael F. Stiefel, Joshua D. Udoetuk, Alejandro M. Spiotta, Vicente H. Gracias, Aaron Goldberg, Eileen Maloney-Wilensky, Stephanie Bloom and Peter D. Le Roux

, Steyerberg EW , Avezaat CJ : CO2 reactivity and brain oxygen pressure monitoring in severe head injury . Crit Care Med 28 : 3268 – 3274 , 2000 11 Chan KW , Miller JD , Dearden NM , Andrews PJ , Midgley S : The effect of changes in cerebral perfusion pressure upon middle cerebral artery blood flow velocity and jugular bulb venous oxygen saturation after severe brain injury . J Neurosurg 77 : 55 – 61 , 1992 12 Changaris DG , McGraw CP , Richardson JD , Garretson HD , Arpin EJ , Shields CB : Correlation of cerebral perfusion

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Anthony A. Figaji, Eugene Zwane, A. Graham Fieggen, Andrew C. Argent, Peter D. Le Roux, Peter Siesjo and Jonathan C. Peter

Czosnyka M , Smielewski P , Lavinio A , Pickard JD , Panerai R : An assessment of dynamic autoregulation from spontaneous fluctuations of cerebral blood flow velocity: a comparison of two models, index of autoregulation and mean flow index . Anesth Analg 106 : 234 – 239 , 2008 11 Czosnyka M , Smielewski P , Piechnik S , Steiner LA , Pickard JD : Cerebral autoregulation following head injury . J Neurosurg 95 : 756 – 763 , 2001 12 Dings J , Meixensberger J , Amschler J , Hamelbeck B , Roosen K : Brain tissue pO 2 in

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Suresh N. Magge, H. Isaac Chen, Rohan Ramakrishna, Liyi Cen, Zhen Chen, J. Paul Elliott, H. Richard Winn and Peter D. Le Roux

tomography scanning and the development of cerebral vasospasm: the Fisher grade revisited . Surg Neurol 63 : 229 – 235 , 2005 55 Topple A , Fifkova E , Cullen-Dockstader K : Effect of age on blood vessels and neurovascular appositions in the rat dentate fascia . Neurobiol Aging 11 : 371 – 380 , 1990 56 Torbey MT , Hauser TK , Bhardwaj A , Williams MA , Ulatowski JA , Mirski MA , : Effect of age on cerebral blood flow velocity and incidence of vasospasm after aneurysmal subarachnoid hemorrhage . Stroke 32 : 2005 – 2011 , 2001 57