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  • Author or Editor: Akira Ogawa x
  • By Author: Kameyama, Motonobu x
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Tomoko Kobayashi, Akira Ogawa, Motonobu Kameyama, Hiroshi Uenohara and Takashi Yoshimoto

✓ A unique case is reported of Chiari malformation and compression of the medulla oblongata by both vertebral arteries. A 39-year-old woman complained of unsteady gait and motor weakness of the legs, and magnetic resonance imaging revealed the malformation and compression. Vascular decompression of the vertebral arteries was performed using synthetic (Gore-tex) vascular strips following posterior fossa decompression.

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Akira Ogawa, Motonobu Kameyama, Kenji Muraishi, Takashi Yoshimoto, Masatoshi Ito and Yoshiharu Sakurai

✓ In order to clarify the effectiveness of extracranial-intracranial bypass operations in patients with vertebrobasilar occlusive disease, the authors used positron emission tomography to investigate the cerebral blood flow (CBF) and metabolism of eight patients undergoing superficial temporal artery (STA)-superior cerebellar artery (SCA) bypass procedures. In the preoperative studies, CBF in the region of the posterior fossa was low and the oxygen extraction fraction (OEF) was high, the so-called “misery perfusion syndrome.” Such changes were evident in both the posterior circulation and the anterior circulation regions. Postoperatively, there was a significant increase in CBF, a significant decrease in the OEF not only in the region of posterior circulation but also over the entire brain, and a disappearance of the uncoupling between CBF and oxygen metabolism. The STA-SCA bypass procedure is effective in improving CBF and metabolism in patients with vertebrobasilar occlusive disease.