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Justin K. Scheer, Justin S. Smith, Aaron J. Clark, Virginie Lafage, Han Jo Kim, John D. Rolston, Robert Eastlack, Robert A. Hart, Themistocles S. Protopsaltis, Michael P. Kelly, Khaled Kebaish, Munish Gupta, Eric Klineberg, Richard Hostin, Christopher I. Shaffrey, Frank Schwab, Christopher P. Ames and the International Spine Study Group

)–Schwab spine deformity class, 24 preoperative pain severity, and patient satisfaction. Methods Patient Cohort This study retrospectively reviewed a prospective multicenter database of ASD patients. Patients were enrolled consecutively and drawn from the International Spine Study Group (ISSG), comprising 11 sites across the United States. All patients were enrolled into an institutional review board–approved protocol by each site, and approval was obtained through each of the sites. Inclusion criteria for the ISSG database were the following: age > 18 years and

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Kseniya Slobodyanyuk, Caroline E. Poorman, Justin S. Smith, Themistocles S. Protopsaltis, Richard Hostin, Shay Bess, Gregory M. Mundis Jr., Frank J. Schwab and Virginie Lafage

-Related Quality of Life Normative Data and Clinical Classifications At BL and 1Y, the health-related quality of life (HRQOL) was evaluated based on the SRS-22 questionnaire. 1 The HRQOL scores for each patient were expressed in terms of minimum clinically important difference (MCID) to standardize data, such that the scores reflected the MCID deviation of each patient from normative values (see Equation). 17 The HRQOL assessment included the SRS-22 domains of Pain, Activity, Appearance, and Mental, but did not include Satisfaction or Total because there are no available

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Joshua Bakhsheshian, Justin K. Scheer, Jeffrey L. Gum, Richard Hostin, Virginie Lafage, Shay Bess, Themistocles S. Protopsaltis, Douglas C. Burton, Malla Kate Keefe, Robert A. Hart, Gregory M. Mundis Jr., Christopher I. Shaffrey, Frank Schwab, Justin S. Smith, Christopher P. Ames and The International Spine Study Group

Society-22r questionnaire (SRS-22r). The SRS-22r provides multiple subdomains (activity, pain, self-image, mental health, and satisfaction with management) and a total score. A numeric rating scale (NRS) score ranging from 0 (no pain) to 10 (worst pain) was individually collected for back and leg pain. Minimal clinically important difference values have been established for HRQOL measurements. 3 , 7 To analyze clinically relevant changes, differences in the proportions of patients reaching the MCID for each HRQOL measure were also evaluated. The MCID values used in the

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Shayan Fakurnejad, Justin K. Scheer, Virginie Lafage, Justin S. Smith, Vedat Deviren, Richard Hostin, Gregory M. Mundis Jr., Douglas C. Burton, Eric Klineberg, Munish Gupta, Khaled Kebaish, Christopher I. Shaffrey, Shay Bess, Frank Schwab, Christopher P. Ames and The International Spine Study Group

Component Summary (PCS) and the Mental Component Summary (MCS) scores. The SRS-22 provides a total score and those from 5 subdomains, including activity, pain, self-image, mental, and satisfaction. To increase the clinical applicability of the HRQOL outcomes, MCID values for these measures have been previously established. 4 , 9 , 10 , 12 The SCB values for the ODI score and the PCS score have also been established and were considered for the current study. 12 The MCID and SCB values used in the present study were as follows: an ODI score MCID of −15 and an ODI score

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Justin K. Scheer, Virginie Lafage, Justin S. Smith, Vedat Deviren, Richard Hostin, Ian M. McCarthy, Gregory M. Mundis, Douglas C. Burton, Eric Klineberg, Munish C. Gupta, Khaled M. Kebaish, Christopher I. Shaffrey, Shay Bess, Frank Schwab, Christopher P. Ames and the International Spine Study Group (ISSG)

(SF-36, physical component score [PCS] and mental component score [MCS]), and the Scoliosis Research Society-22 questionnaire (SRS, subdomains: activity, pain, satisfaction, mental, appearance, and total), were used to evaluate patients preoperatively and 1 and 2 years postoperatively. Differences and correlations between age groups for HRQOLs at the standard preoperative time and follow-up time points were investigated. Furthermore, the change in HRQOL at the postoperative time points versus preoperative values was compared across surgery and age groups. Changes in

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Taemin Oh, Justin K. Scheer, Justin S. Smith, Richard Hostin, Chessie Robinson, Jeffrey L. Gum, Frank Schwab, Robert A. Hart, Virginie Lafage, Douglas C. Burton, Shay Bess, Themistocles Protopsaltis, Eric O. Klineberg, Christopher I. Shaffrey, Christopher P. Ames and the International Spine Study Group

ASD Variable All Patients, n = 234 +MCID, n = 129 −MCID, n = 105 p Value ODI 46.5 ± 14.8 48.3 ± 14.2 44.3 ± 15.3 0.038 * PCS 30.0 ± 8.0 30.0 ± 7.5 30.4 ± 8.7 0.517 MCS 44.5 ± 14.1 44.0 ± 14.7 45.2 ± 13.2 0.581 SRS-22r  Activity 2.8 ± 0.8 2.8 ± 0.8 2.8 ± 0.7 0.572  Pain 2.3 ± 0.7 2.3 ± 0.7 2.3 ± 0.8 0.993  Appearance 2.3 ± 0.7 2.3 ± 0.7 2.3 ± 0.7 0.795  Mental 3.4 ± 0.9 3.4 ± 0.9 3.4 ± 1.0 0.617  Satisfaction 2.8 ± 1.1 2.7 ± 1.1 2.9 ± 1.1 0.224  Total 2.7 ± 0.6 2.7 ± 0.6 2.7 ± 0.6 0.799 Frailty index 3.7 ± 0.9 3.6 ± 0.9 3.7 ± 0.8 0.419 Frailty index category 1.4 ± 0

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Justin K. Scheer, Jessica A. Tang, Justin S. Smith, Eric Klineberg, Robert A. Hart, Gregory M. Mundis Jr., Douglas C. Burton, Richard Hostin, Michael F. O'Brien, Shay Bess, Khaled M. Kebaish, Vedat Deviren, Virginie Lafage, Frank Schwab, Christopher I. Shaffrey, Christopher P. Ames and the International Spine Study Group

1-year SRS-22 scores, the Reop Within 1 Year Group had significantly lower scores than the No Reop Group for the activity (3.2 ± 1.0 vs 3.6 ± 0.9, p = 0.0418), appearance (3.3 ± 1.1 vs 3.8 ± 0.8, p = 0.0286), and pain (31. ± 1.1 vs 3.5 ± 1.0, p = 0.0469) subcategories as well as significantly lower total scores (3.4 ± 0.9 vs 3.70.8, p = 0.0351; Fig. 2 ). There was no statistically significant difference between the 2 groups with respect to the mental or satisfaction subcategory scores (p > 0.05). Furthermore, the Reop Within 1 Year Group had a significantly

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Alex Soroceanu, Douglas C. Burton, Bassel Georges Diebo, Justin S. Smith, Richard Hostin, Christopher I. Shaffrey, Oheneba Boachie-Adjei, Gregory M. Mundis Jr., Christopher Ames, Thomas J. Errico, Shay Bess, Munish C. Gupta, Robert A. Hart, Frank J. Schwab, Virginie Lafage and International Spine Study Group

adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013 . Lancet 384 : 766 – 781 , 2014 45 Park P , Upadhyaya C , Garton HJ , Foley KT : The impact of minimally invasive spine surgery on perioperative complications in overweight or obese patients . Neurosurgery 62 : 693 – 699 , 2008 46 Passias PG , Yang S , Soroceanu A , Smith SJ , Shaffrey C , Boachie-Adjei O , : Predictors of revision surgery in adult spinal deformity and impact on patient-reported outcomes and satisfaction: two-year follow

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David B. Bumpass, Lawrence G. Lenke, Jeffrey L. Gum, Christopher I. Shaffrey, Justin S. Smith, Christopher P. Ames, Shay Bess, Brian J. Neuman, Eric Klineberg, Gregory M. Mundis Jr., Frank Schwab, Virginie Lafage, Han Jo Kim, Douglas C. Burton, Khaled M. Kebaish, Richard Hostin, Renaud Lafage, Michael P. Kelly and for the International Spine Study Group

.6   D 20.2 29.6  Pelvic tilt modifier 0.69   <20° 42 37.2   20–30° 35.2 36.9   >30° 22.7 25.9  Global alignment modifier 0.43   SVA <4 cm 39.5 45.6   SVA 4–9.5 cm 31.4 24.8   SVA >9.5 cm 29.1 29.6  Pelvic incidence–lumbar lordosis modifier 0.89   <10° 40.9 42.7   10–20° 22.7 20.4   >20° 36.4 36.9 HRQOL outcomes  ODI 43.2 (1.8) 42.4 (1.1) 0.72  SRS-22r   Activity 2.8 (0.1) 2.9 (0.1) 0.42   Pain 2.4 (0.1) 2.5 (0.1) 0.24   Appearance 2.5 (0.1) 2.4 (0.04) 0.20   Mental 3.4 (0.1) 3.4 (0.1) 0.61   Satisfaction 2.6 (0.1) 2.7 (0.1) 0.43   Total 2.8 (0.1) 2.8 (0.03) 0.56  SF

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Justin S. Smith, Manish Singh, Eric Klineberg, Christopher I. Shaffrey, Virginie Lafage, Frank J. Schwab, Themistocles Protopsaltis, David Ibrahimi, Justin K. Scheer, Gregory Mundis Jr., Munish C. Gupta, Richard Hostin, Vedat Deviren, Khaled Kebaish, Robert Hart, Douglas C. Burton, Shay Bess and Christopher P. Ames

. Standardized HRQOL measures used were the Oswestry Disability Index, Short Form–36 (SF-36) scores, and Scoliosis Research Society–22 (SRS-22) scores. Two standard summary scores were calculated on the basis of the SF-36: the physical component score and the mental component score. The SRS-22 provides a summary score and multiple subdomains, including activity, pain, appearance, mental, and satisfaction. Full-length free-standing anteroposterior and lateral spine radiographs (36-in cassette) at baseline and 1-year follow-up were analyzed by using validated Spineview