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Constantin Tuleasca, Romain Carron, Noémie Resseguier, Anne Donnet, Philippe Roussel, Jean Gaudart, Marc Levivier and Jean Régis

months after the procedure. The authors discovered acute degenerating axons with some identifiable myelinated axons, small foci of necrosis (including Schwann cell nuclei necrosis), and normal trigeminal ganglion when they used 80 Gy. At 100-Gy doses they found axon degeneration with myelin vacuolation and expansion of the endoneurial intracellular matrix, which was consistent with edema. In one specimen, almost the entire width of the nerve was necrotic. Axon degeneration was noted outside the necrotic zone, but the histological features normalized toward the ganglion

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Jean Régis, Constantin Tuleasca, Noémie Resseguier, Romain Carron, Anne Donnet, Jean Gaudart and Marc Levivier

, Bourgeois S , Farrell JJ , Kasperavičiūtė D , Carrington M , : HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans . N Engl J Med 364 : 1134 – 1143 , 2011 21 Merrison AF , Fuller G : Treatment options for trigeminal neuralgia . BMJ 327 : 1360 – 1361 , 2003 22 Mullan S , Lichtor T : Percutaneous microcompression of the trigeminal ganglion for trigeminal neuralgia . J Neurosurg 59 : 1007 – 1012 , 1983 23 North RB , Kidd DH , Piantadosi S , Carson BS : Percutaneous retrogasserian glycerol