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Christoph J. Griessenauer, Jeffrey D. Lebensburger, Michelle H. Chua, Winfield S. Fisher III, Lee Hilliard, Christina J. Bemrich-Stolz, Thomas H. Howard and James M. Johnston

the University of Alabama at Birmingham and Children’s of Alabama was reviewed retrospectively. A stroke was defined as the new onset of a neurological deficit with correlated ischemic findings on imaging, whereas silent ischemic events were defined as ischemic imaging findings that remained clinically silent. Per the institutional protocol for management of stroke prevention in patients with SCD, a patient is started on chronic transfusion therapy for primary stroke prevention if a time-averaged mean blood flow velocity of ≥ 200 cm/sec in the terminal internal

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Christoph J. Griessenauer, R. Shane Tubbs, Paul M. Foreman, Michelle H. Chua, Nilesh A. Vyas, Robert H. Lipsky, Mingkuan Lin, Ramaswamy Iyer, Rishikesh Haridas, Beverly C. Walters, Salman Chaudry, Aisana Malieva, Samantha Wilkins, Mark R. Harrigan, Winfield S. Fisher III and Mohammadali M. Shoja

.613273 21680905 4 Calviere L , Nasr N , Arnaud C , Czosnyka M , Viguier A , Tissot B , : Prediction of delayed cerebral ischemia after subarachnoid hemorrhage using cerebral blood flow velocities and cerebral autoregulation assessment . Neurocrit Care 23 : 253 – 258 , 2015 10.1007/s12028-015-0125-x 25716738 5 Chalouhi N , Zanaty M , Whiting A , Yang S , Tjoumakaris S , Hasan D , : Safety and efficacy of the Pipeline Embolization Device in 100 small intracranial aneurysms . J Neurosurg 122 : 1498 – 1502 , 2015 10.3171/2014.12.JNS

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Paul M. Foreman, Michelle H. Chua, Mark R. Harrigan, Winfield S. Fisher III, R. Shane Tubbs, Mohammadali M. Shoja and Christoph J. Griessenauer

, 2007 10.1161/STROKEAHA.107.484360 17569871 21 Teasdale G , Jennett B : Assessment of coma and impaired consciousness. A practical scale . Lancet 2 : 81 – 84 , 1974 10.1016/S0140-6736(74)91639-0 4136544 22 Torbey MT , Hauser TK , Bhardwaj A , Williams MA , Ulatowski JA , Mirski MA , : Effect of age on cerebral blood flow velocity and incidence of vasospasm after aneurysmal subarachnoid hemorrhage . Stroke 32 : 2005 – 2011 , 2001 11546889 10.1161/hs0901.094622 23 Yoshimoto Y , Kwak S : Age-related multifactorial causes of