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Ichiro Yuki, Daniel Lee, Yuichi Murayama, Alexander Chiang, Harry V. Vinters, Ichiro Nishimura, Chiachien J. Wang, Akira Ishii, Benjamin M. Wu and Fernando Viñuela

active at both Day 7 and Day 14. However, the patterns showed inversion over time, with protein synthesis–related genes being down-regulated in the Polysorb group compared with the GDC group at Day 7, and upregulated at Day 14. F ig . 8. Graph illustrating the results of EASE functional clustering. Note that specific genes may be related to multiple functional classes. Much of the previous research in the field of vascular biology has focused on two key areas: 1) the molecular biology of cytokines and of chemokines in particular, and 2) the ECM and wound

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Daniel Lee, Ichiro Yuki, Yuichi Murayama, Alexander Chiang, Ichiro Nishimura, Harry V. Vinters, Chiachien J. Wang, Yih-Lin Nien, Akira Ishii, Benjamin M. WU and Fernando Viñuela

genes may be related to multiple classes. Although EASE provides an expression profile of all the significantly changed genes in our model, much of the prior research in the field of vascular biology has focused on two key areas: 1) cytokine/chemokine molecular biology, and 2) ECM/wound healing. Therefore, we compiled a list of 827 genes related to cytokines, chemokines, their receptors, and other immunoregulatory products. We also compiled a list of 109 genes known to produce various cell adhesion molecules, ECM proteins, proteases, and their inhibitors. These