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protect against dioxin action in vivo, with the ultimate goal of identifying a therapeutic approach to improve bone healing in smokers. Neurosurg Focus Neurosurgical Focus FOC 1092-0684 American Association of Neurological Surgeons 2015.4.FOC-LSRSABSTRACTS Abstract Paper # 25. Large Animal Model Development for Use in Testing a Novel Cell Therapy for Degenerative Disc Disease Lara I. Silverman , PhD , Antwain Howard , DVM , and Kevin Foley , MD Semmes-Murphey Neurologic Institute 4 2015 38