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Sergio Cavalheiro, Fábio Veiga de Castro Sparapani, José Orlando Bidó Franco, Marcia Cristina da Silva and Fernando Menezes Braga

A craniopharyngioma is a benign tumor that originates from epithelial rests or from areas of squamous metaplasia related to the hypophysis embryogenesis. These rests may be found in any region of migration from the hypophysiopharyngeal duct, from the tuber cinereum to the sphenoid bone. 5 The tumor may manifest itself in various ways depending on its location, size, and contents. Thus, the therapeutic approach to craniopharyngioma requires a meticulous radiological analysis and careful planning to achieve satisfactory results. We present the case of a

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Neurosurgical Forum: Letters to the editor To The Editor G. Broggi , M.D. , A. Franzini , M.D. Istituto Nazionale Neurologico “C. Besta” Milan, Italy 1080 1081 We read with great interest the paper by Cavalheiro and coworkers (Cavalheiro S, Veiga de Castro Sparapani F, Orlando Bidó Franco J, et al: Use of bleomycin in intratumoral chemotherapy for cystic craniopharyngioma. Case report. J Neurosurg 84: 124–126, January, 1996) in which the therapeutic role of intracavitary bleomycin is

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Sergio Cavalheiro, Fábio Veiga de Castro Sparapani, Antonio Fernandes Moron, Marcia Cristina da Silva and João Norberto Stávale

intracranial neoplasm (craniopharyngioma). J Clin Ultrasound 14 : 304 – 306 , 1986 Snyder JR, Lustig-Gillman I, Milio L, et al: Antenatal ultrasound diagnosis of an intracranial neoplasm (craniopharyngioma). J Clin Ultrasound 14: 304–306, 1986 22. Stout AP , Murray MR : Hemangiopericytoma. A vascular tumor featuring Zimmerman's pericytes. Ann Surg 116 : 26 – 33 , 1942 Stout AP, Murray MR: Hemangiopericytoma. A vascular tumor featuring Zimmerman's pericytes. Ann Surg 116: 26–33, 1942 23. Takaku A

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Maisa Yoshimoto, Sílvia Regina Caminada de Toledo, Nasjla Saba da Silva, Jane Bayani, Ana Paula Antunes Pascalicchio Bertozzi, Joã Norberto Stavale, Sergio Cavalheiro, Joyce Anderson Duffles Andrade, Maria Zielenska and Jeremy A. Squire

the adenohypophysis. 10, 13, 22, 32 In adults these tumors are likely to have a similar histogenesis or may derive from residual papillary squamous epithelium in the adenohypophysis and anterior infundibulum that have undergone metaplasia. 22 Craniopharyngiomas may exhibit a malignant clinical course, despite their benign nature and being composed of well-differentiated tissue classified in two subtypes distinct histologically and clinically: adamantinomatous (embryonic remnants) and papillary (squamous papillary). This pathophysiology aspect is a result of the

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Sergio Cavalheiro, Concezzio Di Rocco, Sergio Valenzuela, Patricia A. Dastoli, Gianpiero Tamburrini, Lucca Massimi, Jardel M. Nicacio, Igor V. Faquini, Daniela F. Ierardi, Nasjla S. Silva, Benedetta Ludovica Pettorini and Silvia R. C. Toledo

Craniopharyngioma is a benign, slow-growing tumor that causes severe disturbances due to involvement of the hypothalamic-pituitary axis and requires a multidisciplinary team for its control. Several therapies have been proposed for patients with CPs, which allows the surgeon to choose the best way to treat each individual patient. 2 The best treatment for this type of tumor is complete removal with preservation of all endocrine and visual functions, which is achieved in a small number of cases. 11 , 12 Curtis et al. 10 reported a low mortality rate after total resection, but

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Shlomi Constantini, Aaron Mohanty, Samuel Zymberg, Sergio Cavalheiro, Conor Mallucci, Dieter Hellwig, Yusuf Ersahin, Hiroshi Mori, Carmelo Mascari, José Aloysio Costa Val, Wolfgang Wagner, Abhaya V. Kulkarni, Spyros Sgouros and Shizuo Oi

Pathology No. (%) low-grade astrocytoma 63 (21.5) high-grade astrocytoma 37 (12.6) germ cell tumor 36 (12.3)  non-secreting germinoma 28 (9.6)  secreting germinoma 5 (1.7)  teratoma 3 (1.0) primitive neuroectodermal tumor 32 (10.9) juvenile pilocytic astrocytoma 29 (9.9) metastases 12 (4.1) craniopharyngioma 9 (3.1) pineocytoma 8 (2.7) lymphoma 6 (2.0) ependymoma 5 (1.7) oligodendroglioma 3 (1.0) other * 25 (8.5) unknown 28 (9.6) * Includes cavernous angioma, granuloma

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Feres Chaddad-Neto, Marcos Devanir Silva da Costa, Baran Bozkurt, Hugo Leonardo Doria-Netto, Daniel de Araujo Paz, Ricardo da Silva Centeno, Andrew W. Grande, Sergio Cavalheiro, Kaan Yağmurlu, Robert F. Spetzler and Mark C. Preul

. Neurosurgery 51 ( 4 Suppl ): S1 – S51 , 2002 14 Santoro A , Salvati M , Vangelista T , Delfini R , Cantore GP : Fronto-temporo-orbito-zygomatic approach and variants. Surgical technique and indications . J Neurosurg Sci 47 : 141 – 147 , 2003 14618127 15 Shirane R , Ching-Chan S , Kusaka Y , Jokura H , Yoshimoto T : Surgical outcomes in 31 patients with craniopharyngiomas extending outside the suprasellar cistern: an evaluation of the frontobasal interhemispheric approach . J Neurosurg 96 : 704 – 712 , 2002 10.3171/jns.2002