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Mohamad Bydon, Rafael De la Garza-Ramos and Ziya L. Gokaslan

consecutive patients . Neurosurgery 71 : 357 – 364 , 2012 2 Fourney DR , Rhines LD , Hentschel SJ , Skibber JM , Wolinsky JP , Weber KL , : En bloc resection of primary sacral tumors: classification of surgical approaches and outcome . J Neurosurg Spine 3 : 111 – 122 , 2005 3 Sahakitrungruang C , Chantra K , Dusitanond N , Atittharnsakul P , Rojanasakul A : Sacrectomy for primary sacral tumors . Dis Colon Rectum 52 : 913 – 918 , 2009 4 Varga PP , Szövérfi Z , Lazary A : Surgical treatment of primary malignant

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Mohammed Adeeb Sebai, Panagiotis Kerezoudis, Mohammed Ali Alvi, Jang Won Yoon, Robert J. Spinner and Mohamad Bydon

mater based on 176 resected tumor cases. 14 Other factors that have been implicated to necessitate the addition of fusion due to extensive resection and increased risk for spinal instability include NF1 status, preexisting deformity, 32 and a diagnosis of malignant PNST. 30 However, in our study we did not find these factors to be significantly linked to or to have an impact on the choice to pursue arthrodesis along with resection. Huang et al. reported primarily a surgical approach for dumbbell-shaped schwannomas in the subaxial cervical spine. In their study all

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Mohamad Bydon, Joseph A. Lin, Rafael de la Garza-Ramos, Daniel M. Sciubba, Jean Paul Wolinsky, Timothy F. Witham, Ziya L. Gokaslan and Ali Bydon

Lunardi P , Acqui M , Ricci G , Agrillo A , Ferrante L : Cervical synovial cysts: case report and review of the literature . Eur Spine J 8 : 232 – 237 , 1999 37 Lyons MK , Birch B : Transoral surgical approach for treatment of symptomatic atlantoaxial cervical synovial cysts . Turk Neurosurg 21 : 483 – 488 , 2011 38 Machino M , Yukawa Y , Ito K , Kato F : Cervical degenerative intraspinal cyst: a case report and literature review involving 132 cases . BMJ Case Rep 2012 bcr2012007126 , 2012 39 Marbacher S , Lukes A

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Rafael De la Garza-Ramos, Risheng Xu, Seba Ramhmdani, Thomas Kosztowski, Mohamad Bydon, Daniel M. Sciubba, Jean-Paul Wolinsky, Timothy F. Witham, Ziya L. Gokaslan and Ali Bydon

Spondylotic Myelopathy Study . J Neurosurg Spine 16 : 425 – 432 , 2012 10 Fengbin Y , Xinwei W , Haisong Y , Yu C , Xiaowei L , Deyu C : Dysphagia after anterior cervical discectomy and fusion: a prospective study comparing two anterior surgical approaches . Eur Spine J 22 : 1147 – 1151 , 2013 11 Fraser JF , Härtl R : Anterior approaches to fusion of the cervical spine: a metaanalysis of fusion rates . J Neurosurg Spine 6 : 298 – 303 , 2007 12 Jack M , Miller J , Hay B , Arnold PM : Long-term outcomes following four

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Kaisorn L. Chaichana, Mohamad Bydon, David R. Santiago-Dieppa, Lee Hwang, Gregory McLoughlin, Daniel M. Sciubba, Jean-Paul Wolinsky, Ali Bydon, Ziya L. Gokaslan and Timothy Witham

incidence of infection in patients older than 65 years. 18 They found that the incidence of infection in this older population was 8.5% for primary surgeries, and the risk of infection was most influenced by increased Charlson comorbidity index, greater than or equal to 9 levels of surgery, and revision surgery, as well as obesity, surgical approach, and year of index procedure. 18 In addition to studies including patients who did not undergo instrumented fusion, several studies have included a significant number of patients with different pathologies 1–3 , 11 , 12

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Matthew J. McGirt, Mohamad Bydon, Kristin R. Archer, Clinton J. Devin, Silky Chotai, Scott L. Parker, Hui Nian, Frank E. Harrell Jr., Theodore Speroff, Robert S. Dittus, Sharon E. Philips, Christopher I. Shaffrey, Kevin T. Foley and Anthony L. Asher

regression models were developed for each PRO measure: disability (ODI), pain (NRS-BP and NRS-LP), and QOL (EQ-5D). Patient-specific variables were included in the models: age, gender, BMI, race, education level, history of surgery, smoking status, comorbid conditions, ASA grade, symptom duration, predominant presenting symptom, workers’ compensation, liability insurance, insurance status, ambulatory ability, and baseline PROs, as well as surgery-specific variables such as number of levels, need for arthrodesis, and surgical approach. We assumed a linear relationship for

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Anthony L. Asher, Clinton J. Devin, Brandon McCutcheon, Silky Chotai, Kristin R. Archer, Hui Nian, Frank E. Harrell Jr., Matthew McGirt, Praveen V. Mummaneni, Christopher I. Shaffrey, Kevin Foley, Steven D. Glassman and Mohamad Bydon

’ propensity for smoking was also significantly associated with higher classification according to the Physical Status Classification System of the American Society of Anesthesiologists (ASA) (p < 0.0001), an anterior-alone surgical approach (p = 0.018), greater number of levels (p = 0.0246), decompression only (p = 0.0001), as well as higher baseline ODI score (p < 0.0001). Figure 2 displays the adjusted and unadjusted importance of each variable included in the multivariable model. The variables that had the greatest association with smoking status were patient age, BMI

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Anthony L. Asher, Clinton J. Devin, Kristin R. Archer, Silky Chotai, Scott L. Parker, Mohamad Bydon, Hui Nian, Frank E. Harrell Jr., Theodore Speroff, Robert S. Dittus, Sharon E. Philips, Christopher I. Shaffrey, Kevin T. Foley and Matthew J. McGirt

-BP and NRS-LP scores), surgery-related variables (surgical approach, fusion, number of levels fused), and comorbidity variables (ASA scores, diabetes, anxiety, depression, osteoporosis, and CAD) were grouped to determine the pooled effect of these variables on RTW. Figure 3 demonstrates the calibration accuracy for RTW estimates based on the model. The bootstrap-validated c-index was 0.71, which suggests that our model is useful in predicting RTW after lumbar spine surgery. Fig. 2. Importance of predictors, measured by Wald chi-square minus the predictor degree of

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Mohammed Abdulaziz, Grant W. Mallory, Mohamad Bydon, Rafael De la Garza Ramos, Jason A. Ellis, Nadia N. Laack, W. Richard Marsh, William E. Krauss, George Jallo, Ziya L. Gokaslan and Michelle J. Clarke

experience of 58 MPE patients treated either with surgery alone or with surgery and adjuvant radiotherapy, specifically noting the surgical approach and factors predicting the resectability of the lesions. Methods The study involved patients with histologically confirmed MPE (WHO Grade I ependymoma) treated at Mayo Clinic Rochester and Johns Hopkins University between 1990 and 2013. Following institutional review board approval, a retrospective review of 107 patients was conducted. Patients of all ages were included, and the minimum follow-up was set at 1 year

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Daniel M. Sciubba, Mohamed Macki, Mohamad Bydon, Niccole M. Germscheid, Jean-Paul Wolinsky, Stefano Boriani, Chetan Bettegowda, Dean Chou, Alessandro Luzzati, Jeremy J. Reynolds, Zsolt Szövérfi, Patti Zadnik, Laurence D. Rhines, Ziya L. Gokaslan, Charles G. Fisher and Peter Paul Varga

Resection and Enneking Appropriateness The EC was known for 26 cases and correlated with the pathologist's postoperative impressions on whether the surgery was EA or EI. All tumors were surgically managed: 10 patients (38%) underwent intralesional resection and 16 (62%) underwent en bloc resection (wide or marginal). The surgical margins were unknown in 1 patient. A posterior approach was performed in 20 patients (77%), an anterior approach in 5 patients (19%), and a combined approach in 1 patient (4%). Surgical approach was not reported in 1 patient. None of the