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Demitre Serletis, Juan Bulacio, William Bingaman, Imad Najm and Jorge González-Martínez

S tereoelectroencephalography (SEEG) is a methodology that permits accurate 3D in vivo electroclinical recordings of epileptiform activity. 1 , 4 , 11 , 17 , 21 , 22 , 30 Among other general indications for invasive intracranial electroencephalography (EEG) monitoring, its advantages include the following: 1) its access to recording from deep cortical structures; 2) its ability to localize the epileptogenic zone when subdural grids have failed to do so; 3) its utility in the context of possible multifocal seizure onsets with the need for bihemispheric

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Sumeet Vadera, Lara Jehi, Richard C. Burgess, Katherine Shea, Andreas V. Alexopoulos, John Mosher, Jorge Gonzalez-Martinez and William Bingaman

reviewed. Eleven patients underwent subdural grid implantation, 23 underwent SEEG, and 31 patients underwent resection with-out any invasive encephalographic studies. Patients were excluded from the study if they did not have at least 6 months of follow-up, if a postoperative MRI study was not available, or if their MEG study was not found to contain any clusters. A cluster was defined in this study as at least 5 dipoles within a 1-cm 2 region, which is the definition that has been used in prior studies. 4 All patients underwent MEG (with the Elekta Neuromag system