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Justin K. Scheer, Justin S. Smith, Frank Schwab, Virginie Lafage, Christopher I. Shaffrey, Shay Bess, Alan H. Daniels, Robert A. Hart, Themistocles S. Protopsaltis, Gregory M. Mundis Jr., Daniel M. Sciubba, Tamir Ailon, Douglas C. Burton, Eric Klineberg, Christopher P. Ames and The International Spine Study Group

T he surgical management of adult spinal deformity (ASD) can provide significant improvements in pain, disability, and health-related quality of life (HRQOL). 6 , 7 , 28 , 34 , 36–38 , 40–45 However, these procedures are technically demanding and are associated with a high complication rate. The patient population suitable for these complicated surgeries continues to increase, including patients of advanced age. 2 , 16 , 17 , 27 The reported complication rates in the literature are varied and range from 14% to 71%. 11 , 13 , 39 , 47 , 48 It has been

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Emily K. Miller, Brian J. Neuman, Amit Jain, Alan H. Daniels, Tamir Ailon, Daniel M. Sciubba, Khaled M. Kebaish, Virginie Lafage, Justin K. Scheer, Justin S. Smith, Shay Bess, Christopher I. Shaffrey, Christopher P. Ames and the International Spine Study Group

predict mortality and self-management ability in nonoperatively treated populations, these indices have recently been shown to be better predictors of perioperative adverse events than chronological age alone. 6 , 11 , 12 , 17 Numerous methods for frailty quantification have been developed and validated. 3 , 4 , 7 , 13 , 15–18 Searle et al. proposed and validated a method for creating frailty indices by using large, existing patient databases. This step-by-step method was used to create a frailty index (the adult spinal deformity frailty index [ASD-FI]) in this study

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Alexander A. Theologis, Tamir Ailon, Justin K. Scheer, Justin S. Smith, Christopher I. Shaffrey, Shay Bess, Munish Gupta, Eric O. Klineberg, Khaled Kebaish, Frank Schwab, Virginie Lafage, Douglas Burton, Robert Hart, Christopher P. Ames and The International Spine Study Group

A dult spinal deformity (ASD) is associated with marked physical and mental impairment. 10 Although evidence exists indicating that surgical treatment improves the quality of life of patients with ASD that causes pain and disability, 18 certain concomitant preoperative medical comorbidities and mental health disorders differentially affect the success of surgical intervention. 16 , 22 For example, prior work from a large population of patients with ASD demonstrated a significantly higher proportion of patients with a history of baseline depression in

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between the two forms of treatment emerge. Neurosurg Focus Neurosurgical Focus FOC 1092-0684 American Association of Neurological Surgeons 2015.3.FOC-DSPNABSTRACTS 103. A Prospective, Multi-Center Assessment of the Best Versus Worst Clinical Outcomes for Adult Spinal Deformity (ASD) Surgery Justin S. Smith , MD PhD , Christopher I. Shaffrey , MD FACS , Virginie Lafage , PhD , Frank Schwab , MD, PhD , Themistocles Protopsaltis , MD , Eric Klineberg , MD , Munish

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the total 511 patients, 502 (98.24%) presented with back pain, 376 (74.17%) with radiculopathy, 76 (14.87%) with motor weakness, and 32 (6.26%) with pre-operative bowel/bladder dysfunction. An average of 2.04 1.03 spinal levels were fused. Post-operatively, patients experienced a significant improvement in back pain (p<0.0001) and radiculopathy (p<0.0001). Patients with fusions excluding the sacrum (floating fusions) were statistically more likely to develop ASD compared with those with fusion constructs ending at S1 distally (p=0.030), but less likely to develop

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systematically distribute any published materials without written permission from JNSPG. 2017 Background/Introduction: Adult spinal deformity (ASD) surgery is a massive undertaking that may involve a significant amount of blood loss, especially when various osteotomy techniques are utilized. Antifibrinolytic agents such as tranexamic acid (TXA) have been used in an attempt to reduce intraoperative blood loss. However, there is no universally accepted dosing protocol for TXA in spine surgery. Moreover, there are very few reports in the literature regarding high

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Background/Introduction: Pseudarthrosis after adult spinal deformity (ASD) surgery may result in instrumentation failure and need for revision. However, the correlation between fusion grade with or without rod fractures and HRQoL is not known. We assessed the association between HRQoL, fusion grade, and rod fracture with and without revision surgery. Materials/Methods: A prospective, multi-center ASD database with 2 year followup data was reviewed. Fusion grade was determined on plain films using published criteria; Grade III or IV at one or more segments was

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ABSTRACTS Abstracts 619. Development of a Preoperative Predictive Model for Intra- or Peri-operative Major Complications with High Accuracy Validated with 558 ASD Patients Christopher Pearson Ames , MD, FAANS , Justin Scheer , BS , Justin Smith , MD, PhD , Frank Schwab , MD , Virginie Lafage , PhD , Christopher Shaffrey , MD , Robert Bess , MD , Tamir Ailon , MD, MPH , Douglas Burton , MD , Eric Klineberg , MD , and International Spine Study Group , (San