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Oral Presentations

2010 AANS Annual Meeting Philadelphia, Pennsylvania May 1–5, 2010

, Canada) 8 2010 113 2 A420 A420 This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose. 2010 Introduction: Our previous studies on a mouse model showed that endothelial nitric oxide synthase (eNOS)/nitric oxide (NO) uncoupling plays a role in vasospasm after subarachnoid hemorrhage (SAH). Simvastatin may decrease vasospasm in both patients and an animal model of SAH. This study investigated the link between the beneficial effect of simvastatin with eNOS/NO uncoupling