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Karl-Fredrik Lindegaard, Søren Jacob Bakke, Peter Grolimund, Rune Aaslid, Peter Huber, and Helge Nornes

dimensionless parameter, the pulsatility index (PI), for quantifying Doppler waveforms. The PI is the amplitude of the flow velocity waveform, or spectrum outline, divided by its timemean value ( Fig. 1 left ). Since systemic cardiovascular characteristics differ between individuals, the PI also varies considerably. 11 In the present study, the pulsatility transmission index (PTI) was introduced to correct for individual variation. The PTI is the PI measured for the MCA under study (PI mca ), expressed as a percentage of the PI for another basal cerebral artery with