Search Results

You are looking at 1 - 10 of 88 items for :

  • Refine by Access: all x
Clear All
Free access

Evaluating risk of recurrence in patients with meningioma

Jeffrey I. Traylor, Aaron R. Plitt, William H. Hicks, Tabarak M. Mian, Bruce E. Mickey, and Samuel L. Barnett

M eningiomas are the most common nonmalignant intracranial tumor and comprise one-third of all tumors of the CNS. 1 WHO classifies meningiomas into three categories according to various histopathological features, with additional molecular biomarkers, which reflect clinical behavior, in the 2021 classification. 2 The vast majority of meningiomas are WHO grade I and are successfully managed with resection alone, whereas grade II and III tumors exhibit higher rates of recurrence and need for adjuvant therapy. 3 Despite an ostensibly benign course, a

Open access

Pediatric meningioma with rhabdoid features developed at the site of skull fracture: illustrative case

Sho Takata, Akira Tamase, Yasuhiko Hayashi, Osamu Tachibana, Katsuaki Sato, and Hideaki Iizuka

Meningiomas account for approximately 20% of intracranial tumors and typically occur in adults. Pediatric meningiomas are rare, and their occurrence is reported to occur in 2.2% of all intracranial meningiomas. They tend to be associated with atypical locations, higher histopathological grades, and aggressive behaviors. 1 Tumorigenesis of a meningioma after head trauma has been deliberated upon for many years. 2–4 In 1938, post-traumatic meningioma was first described by Cushing and Eisenhardt, who reported a causal relationship between head trauma

Open access

Intratumoral abscess complicating a postradiation-induced World Health Organization grade II meningioma: illustrative case

Katherine Callahan, Isidora Beach, Sadie Casale, John DeWitt, and Bruce Tranmer

Meningiomas are the most commonly diagnosed benign primary brain mass, accounting for more than 35% of all brain neoplasms diagnosed annually. 1 In the Western world, brain abscesses occur at a rate of approximately 4 per 1 million annually and are most commonly due to infection by Staphylococcus or Streptococcus bacteria. 2 Peritumoral abscesses are historically associated with intra- or parasellar tumors and have predominantly originated from direct contact with the prenasal sinuses. 3 However, in most reported cases of meningioma-associated abscess

Open access

The management of symptomatic hyperostotic bilateral spheno-orbital meningiomas: patient series

Lauren Harris, Jarnail S Bal, Evangelos Drosos, Samir Matloob, Nicola Y Roberts, Charlotte Hammerbeck-Ward, Omar Pathmanaban, Gareth Evans, Andrew T King, Scott A Rutherford, Jonathan Pollock, and Alireza Shoakazemi

Spheno-orbital meningiomas (SOMs) are benign tumors that can present incidentally or with proptosis and/or visual impairment. Cosmetic impairment explains their early descriptions, including one of the earliest resections by Durante in 1884. 1 Visual symptoms include loss of color vision, deficits of acuity or fields from optic nerve or chiasmal compression, papilledema, diplopia, ptosis, and exophthalmos. 2–4 The tumors are usually slow-growing and can involve the lesser wing of the sphenoid, orbital wall, or orbital roof, with extension into the superior

Open access

Intraoperative MRI for the microsurgical resection of meningiomas close to eloquent areas or dural sinuses: patient series

Constantin Tuleasca, Rabih Aboukais, Quentin Vannod-Michel, Xavier Leclerc, Nicolas Reyns, and Jean-Paul Lejeune

Meningiomas are the most commonly encountered nonglial primary intracranial tumors, with an incidence of approximately 20% of all intracranial tumors. 1 They are more frequent in adults during the fourth through sixth decades of life. 2 , 3 The clinical presentation is variable, unspecific, and depends on tumor anatomical location. 1 Magnetic resonance imaging (MRI) is currently considered the imaging technique of choice and allows assessment of potential mass effect, vascular supply, or degree of the peritumoral edema, as well as accurate localization of

Open access

Fluorescence and immune-cell infiltration of nonneoplastic, postbrachytherapy brain tissue in 5-ALA–guided resection of recurrent anaplastic meningioma: illustrative case

Rishab Ramapriyan, Victoria E Clark, 1 PhD, Maria Martinez-Lage, Brian Hsueh, 1 PhD, Brian V Nahed, 1 MSc, William T Curry, Bryan D Choi, 1 PhD, Bob S Carter, and 1 PhD

5-Aminolevulinic acid (5-ALA) fluorescence-guided surgery (FGS) has gained prominence in recent years for its utility in high-grade glioma resection, allowing enhanced visualization and tumor removal. 1 The use of 5-ALA for meningioma surgery has also been reported. 2 Mechanistically, 5-ALA is preferentially taken up by cells of certain tumors, including meningiomas, and enters the heme biosynthesis pathway, where it is converted to heme precursor porphyrin PpIX, which then accumulates in cells due to various tumor-specific aberrations, such as altered

Open access

Diplopia outcomes following stereotactic radiosurgery for petroclival or cavernous sinus meningiomas: patient series

Bennett R. Levy, Assaf Berger, and Douglas Kondziolka

Skull base meningiomas (SBMs), including petroclival and cavernous sinus meningiomas, comprise 35%–50% of all intracranial meningiomas seen clinically. Upon expansion, they can apply pressure onto cranial nerves (CNs), causing symptoms that vary among facial numbness, pain, muscle weakness, and diplopia. 1 This study focused primarily on meningioma-related diplopia and its resolution following GKS on the offending lesion. These tumors, located in the cavernous sinus, clivus, or petroclival regions, pose a difficult challenge for maximal resection because of

Open access

Paramedian transparietal approach to a dominant hemisphere intraventricular meningioma: illustrative case

John P. Andrews, Tarun Arora, Philip Theodosopoulos, and Mitchel S. Berger

Intraventricular meningiomas are relatively rare entities, 1 , 2 but when they do occur, they are often large and most commonly found in the atria of the lateral ventricle, with a slight predilection for the left side. 3 Series from as recently as the 1980s showed high morbidity and even mortality associated with intraventricular meningiomas, 4 with mortalities due mostly to postoperative intraventricular hemorrhage. More recent series, however, show that these tumors can be removed safely with good outcome. 5–7 Interhemispheric transcallosal, temporal

Open access

Cerebral arterial vasospasm complicating supratentorial meningioma resection: illustrative cases

Andrew C Pickles, John T Tsiang, Alexandria A Pecoraro, Nathan C Pecoraro, Ronak H Jani, Brandon J Bond, Anand V Germanwala, Joseph C Serrone, and Vikram C Prabhu

Meningiomas are the most frequently diagnosed primary tumor of the central nervous system. 1 , 2 Resection of meningiomas is the first-line treatment, with the extent of removal being inversely related to the rate of recurrence. 3 Preservation of the arachnoid plane around a meningioma facilitates a more complete resection with avoidance of injury to the adjacent cortex. However, at times, pial or brain invasion may complicate identification of the tumor margin. 4 In addition, meningiomas parasitize pial and cortical vessels and can be densely adherent

Free access

Contralateral subfrontal approach for tuberculum sellae meningioma: techniques and clinical outcomes

Yeong Jin Kim, Kyung-Sub Moon, Woo-Youl Jang, Tae-Young Jung, In-Young Kim, and Shin Jung

T uberculum sellae meningiomas (TSMs) are challenging tumors given their proximity to the optic nerve, internal carotid artery (ICA), anterior cerebral artery (ACA), and infundibulum. Almost all TSMs invade the optic canal and displace the optic nerve superiorly and laterally, causing visual impairment. 1 Consequently, complete tumor removal and the preservation of visual function without complications are the important goals of TSM treatment. Various surgical approaches are currently used for the treatment of TSMs. Both transcranial and transsphenoidal