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Chronic lymphocytic leukemia/small lymphocytic lymphoma arising in the pituitary gland: illustrative case

Hang Zhou, Xiaowei Zhang, Xin Jia, Liang Jia, and Qingjiu Zhang

.1%), meningiomas (0.94%), metastatic tumors (0.6%), and chordomas (0.5%), although other rare lesions have also been detected (6.0% in total). 1–3 Primary central nervous system lymphoma is relatively rare. Because of the absence of intracranial lymphoid structures, it is now generally accepted that the lesions originate from primitive mesenchymal cells of the ventricular ectoderm, soft meningeal histiocytes, and microglia and that they are predominantly non-Hodgkin’s lymphomas, most often of B-cell origin. The majority of lesions occur in the brain parenchyma, spinal cord

Open access

A sellar-suprasellar malignant optic pathway glioblastoma in the absence of prior radiation therapy: illustrative case

Mestet Yibeltal Shiferaw, Tsegazeab Laeke Teklemariam, Abenezer Tirsit Aklilu, Dejen Teke Gebrewahd, Bereket Hailu Mekuria, Ermias Fikru Yesuf, and Taye Jemberu Robele

-grade glioma. 6 , 12 This finding contrasts with our case, because our patient presented at 19 years of age; it is an extremely rare event for a GBM to develop elsewhere in the brain let alone the sellar-suprasellar area. The differential diagnosis includes pituitary adenomas, the most common tumors in the sellar region, followed by craniopharyngiomas and Rathke cleft cysts and, less commonly, meningiomas, germinomas, hamartomas, and metastatic tumors. On the contrary, malignant sellar gliomas are very rare, and only a few cases of suprasellar malignant gliomas have been