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Bone formation in custom-made cranioplasty: evidence of early and sustained bone development in bioceramic calcium phosphate implants. Patient series

Jimmy Sundblom, Fabjola Xheka, Olivera Casar-Borota, and Mats Ryttlefors

findings proving the integration of implants with existing bone. Study Description Four patients with preexisting CaP implants undergoing anatomically adjacent procedures or redo surgery for reasons unrelated to IF were recruited from the neurosurgical department at Uppsala University Hospital. Ages are reported according to the time of the original cranioplasty procedure. Case 1 Case 1 has been reported previously. 11 The patient was a 39-year-old female with a giant intraosseous chordoid meningioma undergoing removal and repair of a large defect with a

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Extensive extracranial growth of spheno-orbital meningioma: illustrative case

Makoto Saito, Shinjitsu Nishimura, Sumito Okuyama, Keiichi Kubota, Junko Matsuyama, Atsuhito Takemura, Tadao Matsushima, Hideo Sakuma, and Kazuo Watanabe

Meningiomas are the most common benign tumors arising from the central nervous system and are approximately twice as common in women as in men. 1 World Health Organization (WHO) grade 2 and 3 meningiomas show a higher rate of brain involvement and recurrence than their grade 1 counterparts. 2 The MIB-1 index and Ki-67 index are used as proliferation markers, with higher values suggesting a higher WHO grade. 3 , 4 Spheno-orbital meningiomas (SOMs) are rare brain tumors arising from the sphenoidal ridge on the sphenoid wing and can be divided into

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Three decades of progress from surgery to medical therapy for isolated neuroaxis BRAF V600E–positive Langerhans cell histiocytosis management: illustrative case

Nallammai Muthiah, Kamil W. Nowicki, Jennifer L. Picarsic, Michael P. D’Angelo, Daniel F. Marker, Edward G. Andrews, Edward A. Monaco III, and Ajay Niranjan

without contrast. T2, FLAIR, and T1 c+ showing new parietal dural-based lesion ( red circle ). FIG. 3. A: MRI with and without contrast. T2, FLAIR, and T1 c+ showing mass effect and edema from right parietal dural lesion ( red circle ). B: MRI with and without contrast. T2, FLAIR, and T1 c+ showing resolved mass effect and edema 1 year after parietal meningioma resection. A left frontal meningioma was also noted ( red circle ). After discussion with her primary caregivers, the decision was made to resect the new lesion via a right frontotemporal

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Intraosseous meningioma, a rare presentation of a common brain tumor: illustrative case

Sherif Elwatidy, Abdulaziz Alanazi, Rahaf F. Alanazi, and Khulood K. Alraddadi

Meningioma, also known as meningeal tumor, is a benign tumor that is typically slow growing. 1 , 2 It originates from the arachnoid cap cells from a highly metabolic active subtype that is involved in cerebrospinal fluid (CSF) resorption. 1 , 2 It is estimated to account for between 13% and 26% of all intracranial tumors, whereas extradural meningiomas constitute from 1% to 2% of all meningiomas. 2 Intraosseous meningioma is a subgroup of meningioma that arises in the skull. It can occur at any location of the skull, with the orbital cavity and

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“Winged” Eagle’s syndrome: neurophysiological findings in a rare cause of spinal accessory nerve palsy. Illustrative cases

Eric C Mitchell, Kitty Y Wu, Fawaz Siddiqi, John Yoo, Pavlo Ohorodnyk, Douglas Ross, and Thomas A Miller

the trapezius and sternocleidomastoid muscles, indicating a proximal compression point. Advanced imaging, such as CT with three-dimensional reconstruction and MRI, was helpful in excluding other causes of extrinsic SAN compression, such as a glomus tumor or meningioma. In these cases of SAN compression from an angulated or calcified styloid process, surgical decompression and styloidectomy led to good results with the recovery of trapezius function despite the prolonged degree of muscle atrophy. It is unclear if the patients will regain significant middle and