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Bifocal germ cell tumor of pineal germinoma and neurohypophyseal embryonal carcinoma: illustrative case

Yu Naruse, Shinya Jinguji, Ryo Hiruta, Ayako Toda, Kenichiro Nagai, Shingo Kudo, Hideki Sano, Rei Sekine, Osamu Suzuki, Mudathir Bakhit, and Masazumi Fujii

hormone; GH = growth hormone; IGF-1 = insulin-like growth factor–1; LH = luteinizing hormone; PRL = prolactin; TSH = thyroid stimulating hormone; T3 = triiodothyronine; T4 = thyroxine. Progress of Treatment Considering the imaging findings and tumor marker values, a diagnosis of GCT was suspected, leading to the decision to perform emergency procedures, including endoscopic third ventriculostomy (ETV), tumor biopsy, and ventricular drainage. During the operation, gross examination of the neurohypophyseal and pineal tumors revealed contrasting characteristics