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Intraspinal pressure and spinal cord perfusion pressure after spinal cord injury: an observational study

Georgios V. Varsos, Melissa C. Werndle, Zofia H. Czosnyka, Peter Smielewski, Angelos G. Kolias, Isaac Phang, Samira Saadoun, B. Anthony Bell, Argyro Zoumprouli, Marios C. Papadopoulos, and Marek Czosnyka

transform. The amplitude of ISP (I1) is derived from the fundamental component (first harmonic) of the pulse wave in the ISP signal. sPRx and sRAP Indices for ISP In TBI, analysis of the ICP waveform using the PRx and RAP indices can aid in the assessment of both cerebrovascular reactivity status and cerebrospinal compensatory reserve, respectively. PRx reflects the ability of the vascular smooth muscle to respond to changes in transmural pressure and is used as a surrogate index of autoregulation. 9 , 24 PRx is calculated as a moving correlation coefficient