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Hyperacute measurement of intracranial pressure, cerebral perfusion pressure, jugular venous oxygen saturation, and laser Doppler flowmetry, before and during removal of traumatic acute subdural hematoma

Bon H. Verweij, J. Paul Muizelaar, and Federico C. Vinas

consciousness during the period of metabolic depression following human traumatic brain injury. J Neurotrauma 17: 389–401, 2000 10.1089/neu.2000.17.389 3. Bouma GJ , Muizelaar JP : Cerebral blood flow, cerebral blood volume, and cerebrovascular reactivity after severe head injury. J Neurotrauma 9 (Suppl 1) : S333 – S348 , 1992 Bouma GJ, Muizelaar JP: Cerebral blood flow, cerebral blood volume, and cerebrovascular reactivity after severe head injury. J Neurotrauma 9 (Suppl 1): S333–S348, 1992 4. Bullock R

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Norepinephrine in cerebrospinal fluid of patients with cerebral vasospasm

Taku Shigeno

J , Salaices M , et al : Cerebrovascular reactivity to noradrenaline and serotonin following experimental subarachnoid hemorrhage. J Neurosurg 53 : 480 – 485 , 1980 Lobato RD, Marín J, Salaices M, et al: Cerebrovascular reactivity to noradrenaline and serotonin following experimental subarachnoid hemorrhage. J Neurosurg 53: 480–485, 1980 10.3171/jns.1980.53.4.0480 15. Lobato RD , Marín J , Salaices M , et al : Effect of experimental subarachnoid hemorrhage on the adrenergic innervation of cerebral

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Potentiating effects of extraluminal oxyhemoglobin to intraluminal 5-hydroxytryptamine in isolated canine internal carotid arteries

Yuichiro Tanaka and Shigetoshi Chiba

. Neurol Med Chir 19: 61–71, 1979 16. Lobato RD , Marín J , Salaices M , et al : Cerebrovascular reactivity to noradrenaline and serotonin following experimental subarachnoid hemorrhage. J Neurosurg 53 : 480 – 485 , 1980 Lobato RD, Marín J, Salaices M, et al: Cerebrovascular reactivity to noradrenaline and serotonin following experimental subarachnoid hemorrhage. J Neurosurg 53: 480–485, 1980 17. Martin W , Villani GM , Jothianandan D , et al : Selective blockade of endothelium

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Association between shunt-responsive idiopathic normal pressure hydrocephalus and alcohol

Thu-Trang Hickman, Matthew E. Shuman, Tatyana A. Johnson, Felix Yang, Rebecca R. Rice, Isaac M. Rice, Esther H. Chung, Robert Wiemann, Megan Tinl, Christine Iracheta, Grace Chen, Patricia Flynn, Mary Beth Mondello, Jillian Thompson, Mary-Ellen Meadows, Rona S. Carroll, Hong Wei Yang, Hongyan Xing, David Pilgrim, E. Antonio Chiocca, Ian F. Dunn, Alexandra J. Golby, and Mark D. Johnson

that hyperlipidemia, diabetes, or other cardiovascular risk factors promote cerebrovascular disease and decreased cerebral blood flow in the deep white matter, and this leads to cognitive and motor dysfunction. Imaging studies have identified microvascular abnormalities in the deep white matter and periventricular areas of the brain in a subpopulation of patients with iNPH. 9 , 18 , 22 , 23 , 25 , 33 , 34 , 40 Cerebral blood flow studies have documented decreased cerebral blood flow and decreased cerebrovascular reactivity in iNPH patients, raising the possibility

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ICP, CPP, and PRx in traumatic brain injury and aneurysmal subarachnoid hemorrhage: association of insult intensity and duration with clinical outcome

Teodor Svedung Wettervik, Anders Hånell, Timothy Howells, Elisabeth Ronne Engström, Anders Lewén, and Per Enblad

to clinical outcome . Neurocrit Care . 2021 ; 34 ( 2 ): 390 – 402 . 33420669 6 Svedung Wettervik T , Howells T , Enblad P , Lewén A . Temporal neurophysiological dynamics in traumatic brain injury: role of pressure reactivity and optimal cerebral perfusion pressure for predicting outcome . J Neurotrauma . 2019 ; 36 ( 11 ): 1818 – 1827 . 30595128 7 Sorrentino E , Diedler J , Kasprowicz M , Critical thresholds for cerebrovascular reactivity after traumatic brain injury . Neurocrit Care . 2012 ; 16 ( 2 ): 258 – 266 . 21964774 8

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Changes in cerebral blood flow during PaCO2 variations in patients with severe closed head injury: comparison between the Fick and transcranial Doppler methods

Aram Ter Minassian, Eliane Melon, Caroline Leguerinel, Carlo Alberto Lodi, Françis Bonnet, and Laurent Beydon

PaCO 2 variations 14 has encouraged the use of TCD ultrasonography to test CO 2 cerebrovascular reactivity. 2, 21 However, in few studies has the validity of using TCD ultrasonography to assess CBF reactivity to CO 2 in patients with severe closed head injury been assessed. In these patients, the heterogeneity of lesions could lead to heterogeneity in CO 2 reactivity between vascular territories, leading to discrepancies between MCAv changes and global CBF changes. Moreover, in patients suffering from head trauma, CO 2 changes can be accompanied by changes in

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The effect of increased intracranial pressure on cerebrovascular hemodynamics

Harry M. Lowell and Byron M. Bloor

response in the total cerebral blood flow (CBF) and the mean transit time (t̄) were measured (Zeirler 32, 33 ). From these data the total cerebral blood volume (CBV) was computed (CBV = CBF × t̄). The cerebrovascular resistances were calculated by the following formulas: total resistance ; ; . It has previously been reported that in man the log of the cerebrovascular resistance (R t ) is a straight line function of the PaCO 2 and the slope of this line is proportional to the cerebrovascular reactivity. 4 Unpublished data indicate that a similar

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Functional magnetic resonance imaging of the visual cortex performed in children under sedation to assist in presurgical planning

Clinical article

Weier Li, Scott D. Wait, Robert J. Ogg, Matt A. Scoggins, Ping Zou, James Wheless, and Frederick A. Boop

, Lou HC : Change of visually induced cortical activation patterns during development . Lancet 347 : 543 , 1996 . (Letter) 10.1016/S0140-6736(96)91175-7 5 Broadway SJ , Ogg RJ , Scoggins MA , Sanford R , Patay Z , Boop FA : Surgical management of tumors producing the thalamopeduncular syndrome of childhood. Clinical article . J Neurosurg Pediatr 7 : 589 – 595 , 2011 10.3171/2011.4.PEDS119 6 Chen Y , Parrish TB : Caffeine's effects on cerebrovascular reactivity and coupling between cerebral blood flow and oxygen metabolism

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Health economics and the search for shunt-responsive symptomatic hydrocephalus in the elderly

John Douglas Pickard, David Spiegelhalter, and Marek Czosnyka

disease is well known. Cerebral auto-regulation in the deep white matter is impaired in NPH 12 but much less globally. Hemispheric cerebrovascular reactivity is inversely related to CSF outflow resistance in patients presenting with the characteristic triad and ventriculomegaly. 4 In summary, there are many different tests requiring various degrees of expertise and expense and none that alone has sufficient sensitivity and specificity. Hence, it is essential to consider all aspects of an individual case including clinical presentation, neuropsychological profile, MR

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Another cause of treatable dementia: rapid cognitive improvement after carotid endarterectomy. Illustrative case

Mohammed Yassaad Oudrhiri, Akio Teranishi, Soshi Gotan, Hideo Nishi, Hiroki Kobayashi, Noriyuki Yahagi, Kaima Suzuki, Hidetoshi Ooigawa, and Hiroki Kurita

; 50 ( 1 ): 5 – 12 . 9 Lattanzi S , Carbonari L , Pagliariccio G , Neurocognitive functioning and cerebrovascular reactivity after carotid endarterectomy . Neurology . 2018 ; 90 ( 4 ): e307 – e315 . 10 Silvestrini M , Paolino I , Vernieri F , Cerebral hemodynamics and cognitive performance in patients with asymptomatic carotid stenosis . Neurology . 2009 ; 72 ( 12 ): 1062 – 1068 . 11 Zhou D , Meng R , Li SJ , Advances in chronic cerebral circulation insufficiency . CNS Neurosci Ther . 2018 ; 24 ( 1 ): 5