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Neurosurgery: a historical prologue to the future
2000 Presidential address
Martin H. Weiss
✓ The author provides a brief history of the genesis of organized neurosurgery and, in particular, the formation and evolution of the American Association of Neurological Surgeons. The legacy of neurosurgery is noted and the author discusses the present and future practice of neurosurgery.
Martin H. Weiss and John A. Jane
Martin H. Weiss and Uros Roessmann
✓ Hydrocephalic animals were given an intraventricular infusion of radioactive colloidal gold and then sacrificed up to 7 weeks after infusion. Histological evaluation revealed progression from a marked hemorrhagic necrosis of choroid plexus vessels and stroma to eventual replacement by fibrous connective tissue, sclerosis, and fibrinous degeneration of stromal vessels. Particulate colloid was found engulfed in perivascular spaces in the subependymal periventricular tissues, but there was no evidence of vascular damage, gliosis, or demyelination. These findings may play a role in decreasing cerebrospinal fluid production.
Martin H. Weiss and William T. Couldwell
Hydranencephaly of Postnatal Origin
Case Report
Martin H. Weiss, Harold F. Young, and Dee E. McFarland
Martin H. Weiss, Frank E. Nulsen, and Benjamin Kaufman
✓ Hydrocephalic dogs treated with intraventricular radioactive colloidal gold showed a sustained decrease in cerebrospinal fluid flow and intraventricular pressure associated with a reversal of progressive hydrocephalus. Gamma scanning and isotopic sampling, however, indicated a more diffuse distribution of the isotope than previously thought, although pathological changes up to 7 weeks post-instillation of the radioactive colloid appeared confined to the choroid plexus.
Martin H. Weiss, Benjamin Kaufman, and David E. Richards
✓ A case of cerebrospinal fluid rhinorrhea developing in a progressively enlarging empty sella is described in which the fistula was successfully obliterated via a transsphenoidal approach. A modification of the standard closure for transsphenoidal hypophysectomy enabled reconstruction of the dural floor of the sella.