Search Results

You are looking at 1 - 1 of 1 items for :

  • "cerebral metabolism" x
  • Refine by Access: all x
  • By Author: Matsuda, Masayuki x
  • By Author: Chee, Anthony N. C. x
Clear All
Restricted access

Central cholinergic control of cerebral blood flow in the baboon

Effect of cholinesterase inhibition with neostigmine on autoregulation and CO2 responsiveness

Minoru Aoyagi, John Stirling Meyer, Vinod D. Deshmukh, Erwin O. Ott, Yukio Tagashira, Yasuo Kawamura, Masayuki Matsuda, Amrit N. Achari, and Anthony N. C. Chee

intracarotid infusion. The drug was infused intravertebrally in a dose of 12.5 µg/kg of body weight, or 25 µg/kg of body weight was infused into the carotid artery. The measurements of cerebral autoregulatory responsiveness and vasomotor reactivity to CO 2 as well as cerebral metabolism were carried out after repeated steady states in a serial manner before and after neostigmine administration. In order to compare the effect of intravertebral infusion to that of intracarotid infusion, the animals were divided into two groups comprising six animals for each arterial route of