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Shirley I. Stiver, Max Wintermark, and Geoffrey T. Manley

traumatic brain injury and regional cerebral blood flow assessed by 99mTc- HMPAO SPECT . Neurol Med Chir (Tokyo) 33 : 7 – 12 , 1993 43 Yamaura A , Sato M , Meguro K , Nakamura T , Uemura K : [Cranioplasty following decompressive craniectomy—analysis of 300 cases.] . No Shinkei Geka 5 : 345 – 353 , 1977 . (Jpn) 44 Yoshida K , Furuse M , Izawa A , Iizima N , Hirano T , Kuchiwaki H , : Dynamics of cerebral metabolism in patients with chronic subdural hematoma evaluated with phosphorous 31 MR spectroscopy before and after surgery

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Laura B. Ngwenya, Catherine G. Suen, Phiroz E. Tarapore, Geoffrey T. Manley, and Michael C. Huang

critically ill patients 8 and has led to safer and more cost-effective transfusion guidelines. Practitioners are reluctant to treat patients with TBI with a restrictive transfusion protocol due to concerns that a lower Hb target could lead to ischemia, secondary brain injury, and thus worse outcomes. 6 , 11 , 16 It has been demonstrated that transfusion of PRBCs increases brain tissue oxygen (PbtO 2 ); however, there is not an associated improvement in cerebral metabolism to support aggressive transfusion. 21 Yamal et al. 20 have shown that although PbtO 2 was

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Guy Rosenthal, J. Claude Hemphill III, Marco Sorani, Christine Martin, Diane Morabito, Michele Meeker, Vincent Wang, and Geoffrey T. Manley

AM , Guillamondegui O , Maloney-Wilensky E , : Reduced mortality rate in patients with severe traumatic brain injury treated with brain tissue oxygen monitoring . J Neurosurg 103 : 805 – 811 , 2005 15 Tolias CM , Reinert M , Seiler R , Gilman C , Scharf A , Bullock MR : Normobaric hyperoxia–induced improvement in cerebral metabolism and reduction in intracranial pressure in patients with severe head injury: a prospective historical cohort-matched study . J Neurosurg 101 : 435 – 444 , 2004 16 Valadka AB , Gopinath SP

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Oral Presentations

2010 AANS Annual Meeting Philadelphia, Pennsylvania May 1–5, 2010