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Reduced mortality rate in patients with severe traumatic brain injury treated with brain tissue oxygen monitoring

Michael F. Stiefel, Alejandro Spiotta, Vincent H. Gracias, Alicia M. Garuffe, Oscar Guillamondegui, Eileen Maloney-Wilensky, Stephanie Bloom, M. Sean Grady, and Peter D. LeRoux

CPP and brain O 2 is not observed in every patient, in large part because autoregulation frequently is disturbed. 39 Results from recent studies have also demonstrated that an increase in brain tissue PO 2 is associated with improved cerebral metabolism. 32, 45 Together these data indicate that it is reasonable to assume that the use of a brain tissue PO 2 monitor and efforts to increase brain O 2 delivery may improve TBI outcome. Brain Tissue PO 2 —Guided Therapy and Outcome Results of this study demonstrate that brain tissue PO 2 —guided treatment is

In Journal of Neurosurgery Volume 103: Issue 5 (Nov 2005)