The authors report the first case of a Wilms tumor (WT) with diffuse anaplasia metastatic to the brain in a 13-year-old girl with a history of neurofibromatosis Type 1. At presentation, the metastatic tumor had radiological features that suggested a meningioma. Histologically it was characterized by striking anaplasia and features similar to the patient's previously resected WT with diffuse anaplasia.
Abbreviations used in this paper: AE1/AE3 = low- and high-molecular-weight cytokeratin; NF1 = neurofibromatosis Type 1; WT = Wilms tumor.
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