Aneurysmal rupture can result in devastating neurological consequences and can be complicated by comorbid disease processes. Patients with autosomal recessive polycystic kidney disease (ARPKD) have a low rate of reported aneurysms, but this may be due to the relative high rate of end-stage illnesses early in childhood. Authors here report the case of a 10-year-old boy with ARPKD who presented with a Hunt and Hess grade V subarachnoid hemorrhage requiring emergency ventriculostomy, embolization, and decompressive craniectomy. Despite initial improvements in his neurological status, the patient succumbed to hepatic failure. Given the catastrophic outcomes of subarachnoid hemorrhage in young patients, early radiographic screening in those with ARPKD may be warranted.
BedersonJBConnollyESJrBatjerHHDaceyRGDionJEDiringerMN: Guidelines for the management of aneurysmal subarachnoid hemorrhage: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association. Stroke40:994–10252009
De BlasiRLasjauniasPRodeschGAlvarezH: Endovascular treatment of a ruptured intracranial arterial aneurysm in a 12-year-old child with recessive polycystic kidney disease. Interv Neuroradiol3:333–3361997
YoshidaHHigashiharaEMaruyamaKNutaharaKNitatoriTMiyazakiI: Relationship between intracranial aneurysms and the severity of autosomal dominant polycystic kidney disease. Acta Neurochir (Wien)159:2325–23302017
ZhouZXuYDelcourtCShanJLiQXuJ: Is regular screening for intracranial aneurysm necessary in patients with autosomal dominant polycystic kidney disease? A systematic review and meta-analysis. Cerebrovasc Dis44:75–822017