Vein of Galen aneurysmal malformations: critical analysis of the literature with proposal of a new classification system

A review

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  • 1 Division of Neurosurgery, Department of Surgery, University of Alabama at Birmingham;
  • 2 Pediatric Neurosurgery, Children's Hospital, Birmingham, Alabama; and
  • 3 Division of Neurological Surgery, Duke University, Durham, North Carolina
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Vein of Galen aneurysmal malformations are a rare and diverse group of entities with a complex anatomy, pathophysiology, and serious clinical sequelae. Due to their complexity, there is no uniform treatment paradigm. Furthermore, treatment itself entails the risk of serious complication. Offering the best treatment option is dependent on an understanding of the aberrant anatomy and pathophysiology of these entities, and tailored therapy is recommended. Herein, the authors review the current concepts related to vein of Galen aneurysmal malformations and suggest a new classification system excluding mesodiencephalic plexiform intrinsic arteriovenous malformations from this group of malformations.

Abbreviations used in this paper:AV = arteriovenous; AVF = AV fistula; AVM = AV malformation; VGAM = vein of Galen aneurysmal malformation.

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Contributor Notes

Address correspondence to: Martin M. Mortazavi, M.D., Division of Neurosurgery, University of Alabama at Birmingham, 1530 3rd Ave. S., Birmingham, AL 35209. email: m_mortazavi@hotmail.com.

Please include this information when citing this paper: published online July 26, 2013; DOI: 10.3171/2013.5.PEDS12587.

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