Glioependymal cyst on the third cranial nerve: case report

Restricted access

Glioependymal cysts are a rare, congenital, and benign condition. The authors report a case of a 2-year-old female patient who presented with a large exophytic glioependymal cyst located in the left cerebral peduncle, which began with a history of deteriorating function of the left third cranial nerve (CN III). A left 3-piece fronto-orbitozygomatic approach and a microsurgical complete excision of the cyst were performed without complications by accessing the midbrain through the perioculomotor entry zone. The patient’s CN III function completely recovered after 3 months. Because there are currently no widely approved and used classification systems for these cysts, their reporting, naming, and classification are quite confusing in the literature. Thus, their origin, classification, and most common locations warrant further investigation. In addition to reporting this case, the authors present their review of the literature.

ABBREVIATIONS CN = cranial nerve.
Article Information

Contributor Notes

Correspondence Marcos Devanir Silva da Costa: Universidade Federal de São Paulo, São Paulo, Brazil. marcoscostaneuro@gmail.com.INCLUDE WHEN CITING Published online October 25, 2019; DOI: 10.3171/2019.8.PEDS19317.Disclosures The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.
Headings
References
  • 1

    Alvord EC JrMarcuse PM: Intracranial cerebellar meningo-encephalocele (posterior fossa cyst) causing hydrocephalus by compression at the incisura tentorii. J Neuropathol Exp Neurol 21:50691962

    • Search Google Scholar
    • Export Citation
  • 2

    Andrews BTHalks-Miller MBerger MSRosenblum MLWilson CB: Neuroepithelial cysts of the posterior fossa: pathogenesis and report of two cases. Neurosurgery 15:91951984

    • Search Google Scholar
    • Export Citation
  • 3

    Ashker LWeinstein JMDias MKanev PNguyen DBonsall DJ: Arachnoid cyst causing third cranial nerve palsy manifesting as isolated internal ophthalmoplegia and iris cholinergic supersensitivity. J Neuroophthalmol 28:1921972008

    • Search Google Scholar
    • Export Citation
  • 4

    Cavalheiro SYagmurlu Kda Costa MDNicácio JMRodrigues TPChaddad-Neto F: Surgical approaches for brainstem tumors in pediatric patients. Childs Nerv Syst 31:181518402015

    • Search Google Scholar
    • Export Citation
  • 5

    Ciricillo SFDavis RLWilson CB: Neuroepithelial cysts of the posterior fossa. Case report. J Neurosurg 72:3023051990

  • 6

    Conrad JWelschehold SCharalampaki Pvan Lindert EGrunert PPerneczky A: Mesencephalic ependymal cysts: treatment under pure endoscopic or endoscope-assisted keyhole conditions. J Neurosurg 109:7237282008

    • Search Google Scholar
    • Export Citation
  • 7

    Dadlani RGhosal NKhetan RHegde AS: Neurenteric cyst of the cerebello-pontine angle in an infant presenting with obstructive hydrocephalus. Neurol India 60:2472492012

    • Search Google Scholar
    • Export Citation
  • 8

    Figueiredo EGNeto HSMarchiori PERosemberg STeixeira MJ: Endodermal cyst of the third cranial nerve. Clin Neurol Neurosurg 114:108810902012

    • Search Google Scholar
    • Export Citation
  • 9

    Friede RLYaşargil MG: Supratentorial intracerebral epithelial (ependymal) cysts: review, case reports, and fine structure. J Neurol Neurosurg Psychiatry 40:1271371977

    • Search Google Scholar
    • Export Citation
  • 10

    Gilles FHRockett FX: Infantile hydrocephalus: retrocerebellar “arachnoidal” cyst. J Pediatr 79:4364431971

  • 11

    Karikari IOGrant GCummings TJPetrella JFuchs HE: Endodermal cyst of the oculomotor nerve. Pediatr Neurosurg 46:1551562010

  • 12

    Morgan MAEnterline DSFukushima TMcLendon RECummings TJ: Endodermal cyst of the oculomotor nerve. Neuroradiology 43:106310662001

    • Search Google Scholar
    • Export Citation
  • 13

    Morigaki RShinno KPooh KHNakagawa Y: Giant glioependymal cyst in an infant. J Neurosurg Pediatr 7:1751782011

  • 14

    Okunaga TTsutsumi KHayashi TNagata I: Endodermal cyst of the oculomotor nerve: case report. Neurosurgery 58:E9942006

  • 15

    Pelkey TJFerguson JE IIVeille JCAlston SR: Giant glioependymal cyst resembling holoprosencephaly on prenatal ultrasound: case report and review of the literature. Ultrasound Obstet Gynecol 9:2002031997

    • Search Google Scholar
    • Export Citation
  • 16

    Shuangshoti SNetsky MG: Neuroepithelial (colloid) cysts of the nervous system. Neurology 16:8871966

  • 17

    Shuangshoti SPitakdamrongwong NPoneprasert BBhavilai DKasantikul V: Symptomatic neuroepithelial cysts in the posterior cranial fossa. Immunohistochemical and electron-microscopic studies. Surg Neurol 30:2983041988

    • Search Google Scholar
    • Export Citation
  • 18

    Singh NCowie RPal PKarabatsou K: Neuroglial cyst of the sacral canal. Case report. J Neurosurg Spine 14:88922011

  • 19

    Tange YAoki AMori KNiijima SMaeda M: Interhemispheric glioependymal cyst associated with agenesis of the corpus callosum—case report. Neurol Med Chir (Tokyo) 40:5365422000

    • Search Google Scholar
    • Export Citation
  • 20

    Turner SJDexter MASmith JEOuvrier R: Primary nerve repair following resection of a neurenteric cyst of the oculomotor nerve. J Neurosurg Pediatr 9:45482012

    • Search Google Scholar
    • Export Citation
  • 21

    van Lindert EHopf NPerneczky A: Endoscopic treatment of mesencephalic ependymal cysts: technical case report. Neurosurgery 43:123412411998

    • Search Google Scholar
    • Export Citation
  • 22

    Wait SDChoi LSTeo C: Neurenteric cyst: an unusual cause of third nerve palsy. Childs Nerv Syst 27:6396412011

  • 23

    Werner MBhatti MTVaishnav HPincus DWEskin TYachnis AT: Isolated anisocoria from an endodermal cyst of the third cranial nerve mimicking an Adie’s tonic pupil. J Pediatr Ophthalmol Strabismus 42:1761792005

    • Search Google Scholar
    • Export Citation
TrendMD
Metrics

Metrics

All Time Past Year Past 30 Days
Abstract Views 167 167 167
Full Text Views 22 22 22
PDF Downloads 19 19 19
EPUB Downloads 0 0 0
PubMed
Google Scholar