Concomitant intraventricular colloid cyst and low-grade astrocytoma of the brainstem in a 16-year-old boy

Case report

View More View Less
  • 1 Department of Neurosurgery, Sina Hospital;
  • | 2 Department of Neurosurgery, Tehran University of Medical Sciences; and
  • | 3 Department of Neurosurgery, Arad General Hospital, Tehran, Iran
Restricted access

Purchase Now

USD  $45.00

JNS + Pediatrics - 1 year subscription bundle (Individuals Only)

USD  $505.00

JNS + Pediatrics + Spine - 1 year subscription bundle (Individuals Only)

USD  $600.00
Print or Print + Online

Multiple primary brain tumors are commonly observed in patients with a history of brain radiation therapy or neurofibromatosis. The concomitant presence of 2 different types of brain tumors in a single location or chamber is a very rare clinical presentation in the absence of such a predisposing factor. The authors report on the case of a 16-year-old boy presenting with different types of brain tumors in 2 ventricular chambers concomitantly. This boy had a medium-sized colloid cyst of the third ventricle and a large fibrillary astrocytoma fungating from the brainstem into the floor of the fourth ventricle. The lesions were successfully excised in 2 separate surgeries. Radiotherapy was used as the adjuvant mode of therapy. There has been no sign of tumor recurrence after 16 months of follow-up. Clinical awareness and recognition of such a combination of tumors is important because they will dictate special treatment strategies depending on the individual biological aggressiveness of each tumor.

JNS + Pediatrics - 1 year subscription bundle (Individuals Only)

USD  $505.00

JNS + Pediatrics + Spine - 1 year subscription bundle (Individuals Only)

USD  $600.00

Contributor Notes

Address correspondence to: Abbas Amirjamshidi, M.D., M.P.H., Department of Neurosurgery, Sina Hospital, Tehran University of Medical Sciences, Box 19585-678, Tehran 19518, Iran. email: abamirjamshidi@yahoo.com.
  • 1

    Buccoliero AM, , Taddei GL, , Caldarella A, , Mennonna P, , Ammannati F, & Taddei A, et al. : Meningioma-primary brain lymphoma association. Neuropathology 24:336340, 2004

    • Search Google Scholar
    • Export Citation
  • 2

    Chahlavi A, , Staugaitis SM, , Yahya R, & Vogelbaum MA: Intracranial collision tumor mimicking an octreotide-SPECT positive and FDG-PET negative meningioma. J Clin Neurosci 12:720723, 2005

    • Search Google Scholar
    • Export Citation
  • 3

    Davis GA, , Fabinyi GC, , Kalnins RM, , Brazenor GA, & Rogers MA: Concurrent adjacent meningioma and astrocytoma: a report of three cases and review of the literature. Neurosurgery 36:599605, 1995

    • Search Google Scholar
    • Export Citation
  • 4

    Drlicek M, , Aichholzer M, , Wurm G, , Bodenteich A, & Fischer J: [Collisiontumour composed of glioblastoma and meningioma-a case report]. Pathologe 25:402405, 2004. (Ger)

    • Search Google Scholar
    • Export Citation
  • 5

    Gelabert M, , Bollar A, , Martinez R, & Allut AG: Coincidence of a frontal lobe astrocytoma and colloid cyst of the third ventricle. Neurochirurgia (Stuttg) 34:6970, 1991

    • Search Google Scholar
    • Export Citation
  • 6

    Harsh GR, , Keating MT, , Escobedo JA, & Williams LT: Platelet derived growth factor (PDGF) autocrine components in human tumor cell lines. J Neurooncol 8:112, 1990

    • Search Google Scholar
    • Export Citation
  • 7

    Hermansson M, , Nistér M, , Betsholtz C, , Heldin CH, , Westermark B, & Funa K: Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation. Proc Natl Acad Sci U S A 85:77487752, 1988

    • Search Google Scholar
    • Export Citation
  • 8

    Jun P, , Garcia J, , Tihan T, , McDermott MW, & Cha S: Perfusion MR imaging of an intracranial collision tumor confirmed by image-guided biopsy. AJNR Am J Neuroradiol 27:9497, 2006

    • Search Google Scholar
    • Export Citation
  • 9

    Karami KJ, , Poulik J, , Rabah R, , Krass J, & Sood S: Simultaneous choroid plexus carcinoma and pilocytic astrocytoma in a pediatric patient. Case report. J Neurosurg Pediatr 5:104112, 2010

    • Search Google Scholar
    • Export Citation
  • 10

    Khalatbari M, , Borghei-Razavi H, , Shayanfar N, , Behzadi AH, & Sepehrnia A: Collision tumor of meningioma and malignant astrocytoma. Pediatr Neurosurg 46:357361, 2010

    • Search Google Scholar
    • Export Citation
  • 11

    Kodet R: [Multiple malformations of the central nervous system, choroid plexus papilloma and intraventricular meningioma]. Cesk Patol 19:5561, 1983. (Czech)

    • Search Google Scholar
    • Export Citation
  • 12

    Mitsos AP, , Konstantinou EA, , Fotis TG, , Lafazanos SA, , Kontogeorgos G, & Georgakoulias NV: Sphenoid wing meningioma and glioblastoma multiforme in collision - case report and review of the literature. Neurol Neurochir Pol 43:479483, 2009

    • Search Google Scholar
    • Export Citation
  • 13

    Nagashima C, , Nakashio K, & Fujino T: Meningioma and astrocytoma adjacent in the brain. J Neurosurg 20:995999, 1963

  • 14

    Nestler U, , Schmidinger A, , Schulz C, , Huegens-Penzel M, , Gamerdinger UA, & Koehler A, et al. : Glioblastoma simultaneously present with meningioma–report of three cases. Zentralbl Neurochir 68:145150, 2007

    • Search Google Scholar
    • Export Citation
  • 15

    Perry A, , Giannini C, , Scheithauer BW, , Rojiani AM, , Yachnis AT, & Seo IS, et al. : Composite pleomorphic xanthoastrocytoma and ganglioglioma: report of four cases and review of the literature. Am J Surg Pathol 21:763771, 1997

    • Search Google Scholar
    • Export Citation
  • 16

    Prayson RA, , Chowdhary S, , Woodhouse S, , Hanson M, & Nair S: Collision of a syncytial meningioma and malignant astrocytoma. Ann Diagn Pathol 6:4448, 2002

    • Search Google Scholar
    • Export Citation
  • 17

    Russell DS, & Rubinstein LJ: Pathology of Tumours of the Nervous System London, Edward Arnold, 1959. 152158

  • 18

    Sanchez-Mejía RO, , Banerjee A, & Gupta N, Supratentorial highgrade gliomas. Tonn JC, , Westphal M, & Rutka JT, et al. : Neuro-Oncology of CNS Tumors Berlin, Springer-Verlag, 2006. 386391

    • Search Google Scholar
    • Export Citation
  • 19

    Suzuki K, , Momota H, , Tonooka A, , Noguchi H, , Yamamoto K, & Wanibuchi M, et al. : Glioblastoma simultaneously present with adjacent meningioma: case report and review of the literature. J Neurooncol 99:147153, 2010

    • Search Google Scholar
    • Export Citation
  • 20

    Tamber MS, & Rutka JT: Pediatric supratentorial high-grade gliomas. Neurosurg Focus 14:2 e1, 2003

  • 21

    Tokunaga T, , Shigemori M, , Hirohata M, , Sugita Y, , Miyagi J, & Kuramoto S: Multiple primary brain tumors of different histological types—report of two cases. Neurol Med Chir (Tokyo) 31:141145, 1991

    • Search Google Scholar
    • Export Citation
  • 22

    Tugcu B, , Kepoglu U, , Gunal M, , Gunaldi O, , Karakaya B, & Demirgil BT: Two distinct primary brain tumors, in same region of the same patient: a case report. J Neurooncol 79:219220, 2006

    • Search Google Scholar
    • Export Citation
  • 23

    Westermark B, , Siegbahn A, , Heldin CH, & Claesson-Welsh L: B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase. Proc Natl Acad Sci U S A 87:128132, 1990

    • Search Google Scholar
    • Export Citation

Metrics

All Time Past Year Past 30 Days
Abstract Views 297 74 2
Full Text Views 55 2 0
PDF Downloads 69 1 0
EPUB Downloads 0 0 0