The successful treatment of children with a primary CNS germ cell tumor can be greatly influenced by the neurosurgeon involved in the diagnostic and therapeutic care of these children. Variability in surgical philosophies no doubt exists due to the relatively infrequent incidence of these tumors, a lack of consensus regarding diagnostic and therapeutic approaches, and the advent of recent surgical innovations. Many of these issues were discussed at the Second International Symposium on Central Nervous System Germ Cell Tumors through presented abstracts and invited presentations. The neurosurgical aspects of these proceedings are summarized here in an effort to present the agreed-upon and debated issues that may confront the pediatric neurosurgeon.
Abbreviations used in this paper: AFP = alpha-fetoprotein; β−HCG = beta subunit-human chorionic gonadotropin; COG = Children's Oncology Group; ETV = endoscopic third ventriculostomy; GCT = germ cell tumor; NGGCT = nongerminomatous GCT.
Address correspondence to: Mark M. Souweidane, M.D., Department of Neurological Surgery, Weill Medical College of Cornell University, 525 East 69th Street, Box 99, New York, New York 10021. email: email@example.com.
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