Skull base aneurysmal bone cyst presenting with hydrocephalus: progressive residuum obliterated by Gamma Knife stereotactic radiosurgery in a pediatric patient

View More View Less
  • 1 Department of Neuroradiology, Royal Hallamshire Hospital, Sheffield, United Kingdom;
  • 2 Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands;
  • 3 The National Centre for Stereotactic Radiosurgery, Royal Hallamshire Hospital, Sheffield; and
  • 4 Department of Paediatric Neurosurgery, Sheffield Children’s Hospital, Western Bank, Sheffield, United Kingdom
Restricted access

Purchase Now

USD  $45.00

JNS + Pediatrics - 1 year subscription bundle (Individuals Only)

USD  $505.00

JNS + Pediatrics + Spine - 1 year subscription bundle (Individuals Only)

USD  $600.00
Print or Print + Online

Aneurysmal bone cysts (ABCs) are an uncommon entity predominantly encountered in the pediatric population. The skull is rarely involved, but these cysts have been reported to arise in the skull base. Traditional treatment has been with surgery alone; however, there is a gathering body of literature that reports alternative treatments that can achieve long-term disease-free survival. However, these therapies are predominantly directed at peripheral skeletal lesions. To the authors’ knowledge, this report is the first to describe long-term follow-up of the efficacy of Gamma Knife stereotactic radiosurgery for treatment of ABC residuum in the skull base that resulted in long-term patient stability and likely ABC obliteration.

ABBREVIATIONS ABC = aneurysmal bone cyst; GKSRS = Gamma Knife stereotactic radiosurgery.

JNS + Pediatrics - 1 year subscription bundle (Individuals Only)

USD  $505.00

JNS + Pediatrics + Spine - 1 year subscription bundle (Individuals Only)

USD  $600.00

Contributor Notes

Correspondence George H. Tse: Royal Hallamshire Hospital, Sheffield, UK. georgetse@doctors.org.uk.

INCLUDE WHEN CITING Published online April 3, 2020; DOI: 10.3171/2020.2.PEDS19755.

Disclosures The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.

  • 1

    Leithner A, Windhager R, Lang S, Aneurysmal bone cyst. A population based epidemiologic study and literature review. Clin Orthop Relat Res. 1999;(363):176179.

    • Search Google Scholar
    • Export Citation
  • 2

    O’Donnell P, Saifuddin A. The prevalence and diagnostic significance of fluid-fluid levels in focal lesions of bone. Skeletal Radiol. 2004;33(6):330336.

    • Search Google Scholar
    • Export Citation
  • 3

    Bonakdarpour A, Levy WM, Aegerter E. Primary and secondary aneurysmal bone cyst: a radiological study of 75 cases. Radiology. 1978;126(1):7583.

    • Search Google Scholar
    • Export Citation
  • 4

    Dinca EB, de Lacy P, Yianni J, Gamma knife surgery for pediatric arteriovenous malformations: a 25-year retrospective study. J Neurosurg Pediatr. 2012;10(5):445450.

    • Search Google Scholar
    • Export Citation
  • 5

    Chalapati Rao KV, Rao BS, Reddy CP, Aneurysmal bone cyst of the skull. Case report. J Neurosurg. 1977;47(4):633636.

  • 6

    Park HY, Yang SK, Sheppard WL, Current management of aneurysmal bone cysts. Curr Rev Musculoskelet Med. 2016;9(4):435444.

  • 7

    Elsayad K, Kriz J, Seegenschmiedt H, Radiotherapy for aneurysmal bone cysts: a rare indication. Strahlenther Onkol. 2017;193(4):332340.

    • Search Google Scholar
    • Export Citation
  • 8

    Wallace MT, Henshaw RM. Results of cement versus bone graft reconstruction after intralesional curettage of bone tumors in the skeletally immature patient. J Pediatr Orthop. 2014;34(1):92100.

    • Search Google Scholar
    • Export Citation
  • 9

    Rossi G, Rimondi E, Bartalena T, Selective arterial embolization of 36 aneurysmal bone cysts of the skeleton with N-2-butyl cyanoacrylate. Skeletal Radiol. 2010;39(2):161167.

    • Search Google Scholar
    • Export Citation
  • 10

    Zhu S, Hitchcock KE, Mendenhall WM. Radiation therapy for aneurysmal bone cysts. Am J Clin Oncol. 2017;40(6):621624.

  • 11

    Marcove RC, Sheth DS, Takemoto S, Healey JH. The treatment of aneurysmal bone cyst. Clin Orthop Relat Res. 1995;(311):157163.

  • 12

    Rowe J, Grainger A, Walton L, Risk of malignancy after gamma knife stereotactic radiosurgery. Neurosurgery. 2007;60(1):6066.

  • 13

    Levivier M, Gevaert T, Negretti L. Gamma Knife, CyberKnife, TomoTherapy: gadgets or useful tools? Curr Opin Neurol. 2011;24(6):616625.

    • Search Google Scholar
    • Export Citation
  • 14

    Canadian Agency for Drugs and Technologies in Health (CADTH). TomoTherapy, Gamma Knife, and CyberKnife therapies for patients with tumours of the lung, central nervous system, or intra-abdomen: a systematic review of clinical effectiveness and cost-effectiveness. CADTH Technol Overv. 2010;1(3):e0119.

    • Search Google Scholar
    • Export Citation
  • 15

    Bush CH, Drane WE. Treatment of an aneurysmal bone cyst of the spine by radionuclide ablation. AJNR Am J Neuroradiol. 2000;21(3):592594.

    • Search Google Scholar
    • Export Citation

Metrics

All Time Past Year Past 30 Days
Abstract Views 74 74 50
Full Text Views 18 18 7
PDF Downloads 18 18 7
EPUB Downloads 0 0 0