Pigmented epithelioid melanocytoma: a rare lytic bone lesion involving intradural extension and subtotal resection in a 14-month-old girl

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  • 1 School of Medicine,
  • 2 Department of Pediatrics, and
  • 3 Department of Radiology, University Medical Center, Texas Tech University Health Sciences Center, Lubbock, Texas
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Pigmented epithelioid melanocytomas (PEMs) are low-grade, intermediate-type borderline melanocytic tumors with limited metastatic potential. To date, PEMs have been treated via gross-total resections. Postoperative recurrence and mortality are rare. This case highlights a unique presentation of a PEM that involved bone destruction and intradural infiltration, which required a subtotal resection. To the authors’ knowledge, this is the first report of a PEM extending through the dura and necessitating subtotal resection, which is contrary to the standard of care, gross-total resection. Surveillance imaging 10 months after resection remained negative for clinical and radiological recurrence.

ABBREVIATIONS NGS = next-generation sequencing; PEM = pigmented epithelioid melanocytoma.

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Contributor Notes

Correspondence Preston D’Souza: Texas Tech University Health Sciences Center School of Medicine, Lubbock, TX. pd3003@gmail.com.

INCLUDE WHEN CITING Published online March 13, 2020; DOI: 10.3171/2020.1.PEDS19359.

Disclosures The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.

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