Authors:M. Burhan Janjua, Sumanth Reddy, William C. Welch, Amer F. Samdani, Ali K. Ozturk, Steven W. Hwang, Angela V. Price, Bradley E. Weprin and Dale M. Swift
Despite the high incidence of pediatric brain tumors, literature is scarce on examining risk of readmission among pediatric patients undergoing resection of intracranial tumors. The authors studied readmission rate following brain tumor surgery to stratify the risk factors of readmissions in this subset of pediatric patients.
Authors:Jonathan Roth, Neal Fischer, David D. Limbrick Jr., Travis CreveCoeur, Liat Ben-Sira and Shlomi Constantini
The study evaluates the need for screening spinal MRI scans in children who undergo resection of low-grade glioma tumors from their posterior fossa. The need (or not) of such scans has clinical and financial implications, and thus reflects the importance of this study.
The authors’ study makes a significant contribution to the literature because it details the treatment of pediatric patients with ATRTs in Japan and shows the limitations of current multimodal treatments, especially craniospinal irradiation. This finding is important because most ATRTs occur in infants and young children.
Authors:Elena I. Fomchenko, E. Zeynep Erson-Omay, Adam J. Kundishora, Christopher S. Hong, Ava A. Daniel, August Allocco, Phan Q. Duy, Armine Darbinyan, Asher M. Marks, Michael L. DiLuna, Kristopher T. Kahle and Anita Huttner
Authors:Joongyub Lee, Seung-Ki Kim, Hee Gyung Kang, Il-Soo Ha, Kyu-Chang Wang, Ji Yeoun Lee and Ji Hoon Phi
The authors evaluate the prevalence of hypertension among moyamoya disease (MMD) patients. It is important because the long-term deleterious effects of hypertension in pediatric MMD patients seem to be inevitable. As a result, a high prevalence of hypertension in pediatric MMD patients was found. Pediatric neurosurgeons ought to predict and prepare for the development of essential hypertension after surgical treatment of MMD.
Authors:Caroline Gewiss, Christian Hagel and Kara Krajewski
The authors shed light on the role of relaxin in cerebral cavernous malformations (CCMs) in adults and children by investigating the endothelial cell expression of relaxin 1, 2, and 3; vascular endothelial growth factor receptor–1 and –2; Ki-67; vascular geometry; and hemorrhage, as well as clinical presentation in 32 patients with surgically resected lesions. They demonstrate, for the first time, that relaxin is associated with CCMs and, hence, identified a new therapeutic target in the treatment of CCMs.
Authors:Melissa A. LoPresti, Vijay M. Ravindra, Monika Pyarali, Eric Goethe, Nisha Gadgil, Kathyrn Wagner, Peter Kan and Sandi Lam
The purpose of this study was to explore outcomes of treatment and factors that predict recurrence to help guide the management of pediatric intracranial arteriovenous malformations (AVMs). The authors conducted a retrospective chart review to identify patients treated with surgical and nonsurgical modalities and compared their outcomes to better understand how many and what types of AVMs recur and what areas of further study can be targeted to reduce recurrence in pediatric patients with AVMs.
Authors:Shabari Girishan, Manjari Tripathi, Ajay Garg, Ramesh Doddamani, Jitin Bajaj, Bhargavi Ramanujam and P. Sarat Chandra
The authors used postoperative MRI along with diffusion tensor imaging in patients with drug-resistant epilepsy to investigate the role of residual temporal stem connections in recurrent seizures following endoscopic vertical approach hemispherotomy and used cadaveric studies to determine how this problem may be avoided. This study is important in identifying the problem of residual temporal stem during hemispheric disconnection, determining how to identify this problem during surgery, and identifying the role of repeat surgery if seizures are not controlled.
Authors:Carrie R. Muh, Naomi D. Chou, Shervin Rahimpour, Jordan M. Komisarow, Tracy G. Spears, Herbert E. Fuchs, Sandra Serafini and Gerald A. Grant
The authors used direct brain stimulation to find the locations of language, as both seen and heard, in pediatric patients undergoing brain surgery. These findings are helpful to compare to previously reported adult language mapping results and are important to consider when removing brain lesions that are in and around these important sites in pediatric patients.
Authors:Rebekah Marsh, Daniel D. Matlock, Julie A. Maertens, Alleluiah Rutebemberwa, Megan A. Morris, Todd C. Hankinson and Tellen D. Bennett
The authors interviewed parents of children with traumatic brain injury (TBI) and clinicians who care for these children and asked what role parents should play in deciding whether or not to place an intracranial pressure monitor (ICP) in the child's skull. Important findings were that parents and clinicians agreed that decision making about ICP monitoring in children with TBI is the clinicians’ role, which should not be shared with the parents, while parent needs were to be informed and also be included as observers of the process of multidisciplinary decision making by the clinician teams.
Authors:Osama N. Kashlan, D. Andrew Wilkinson, Hal Morgenstern, Siri S. Khalsa and Cormac O. Maher
The authors studied the management of children with a congenital spinal cord anomaly and found that there are differences in the care these patients receive depending on where they live, how sick they generally are, and whether they have an abnormal fluid collection in the spinal cord. This study is important because it sheds light on these differences in a condition that has not been studied as deeply before.
Authors:Kelsey Hayward, Sabrina H. Han, Alexander Simko, Hector E. James and Philipp R. Aldana
Telemedicine has a growing role in providing access to neurosurgical care in underserved communities. The authors studied the socioeconomic benefits of having a pediatric neurosurgery telemedicine clinic and quantified the cost savings to families. They calculated average cost savings as a function of distance from the telemedicine and main clinics.