Authors:Jonathan E. Martin, Brandon G. Rocque, Andrew Jea, Richard C. E. Anderson, Joshua Pahys and Douglas Brockmeyer
The authors established a standard technique for measuring movement of the junction of the head and spine in patients with Down syndrome. This technique will allow doctors to describe mobility of the upper spine in a consistent way in order to help with determining when and how to treat these children with activity restriction or surgery.
Authors:Joyce Koueik, Carolina Sandoval-Garcia, John R. W. Kestle, Brandon G. Rocque, David M. Frim, Gerald A. Grant, Robert F. Keating, Carrie R. Muh, W. Jerry Oakes, Ian F. Pollack, Nathan R. Selden, R. Shane Tubbs, Gerald F. Tuite, Benjamin Warf, Victoria Rajamanickam, Aimee Teo Broman, Victor Haughton, Susan Rebsamen, Timothy M. George and Bermans J. Iskandar
The most effective surgical technique aimed at treating Chiari malformation type I with syringomyelia remains controversial, with options ranging from bone-only posterior fossa decompression (PFD) to PFD with duraplasty (PFDD) and to PFDD with tonsillar reduction (PFDD-T). This is an 8-center prospective study comparing PFDD and PFDD-T, demonstrating feasibility and challenges and presenting pilot data that show no significant advantage to tonsillar reduction.
Authors:Soliman Oushy, Avital Perry, Christopher S. Graffeo, Aditya Raghunathan, Lucas P. Carlstrom and David J. Daniels
This report outlines a single-institution experience with ganglioglioma of the brainstem in pediatric patients in order to highlight the complex treatment challenges and explore novel treatment avenues such as targeting BRAF V600E via vemurafenib.
Authors:Ros Whelan, Eric Prince, David M. Mirsky, Robert Naftel, Aashim Bhatia, Benedetta Pettorini, Shivaram Avula, Susan Staulcup, Allyson L. Alexander, Maxene Meier and Todd C. Hankinson
In this study, the authors investigated the interrater reliability of a commonly used system for grading pediatric craniopharyngiomas that helps plan the surgical approach. This study shows that the interrater reliability is moderate and that the generalizability of the system is questionable. The paper highlights the need to continue to develop systems that aid the surgeon and team in planning the appropriate treatment plan for patients.
Authors:Steffen Fleck, Sascha Marx, Clara Bobak, Victoria Richter, Stephan Nowak, Ehab El Rafaee, Nikolai Siebert, Karoline Ehlert, Henry W. S. Schroeder and Holger N. Lode
This is a retrospective single-center analysis of all neurosurgical strategies for the treatment of cranial and intracerebral metastases in pediatric patients diagnosed with neuroblastoma. The study reports the largest series of neurosurgical resections of cranial and intracerebral neuroblastoma metastases to date.
Authors:Andrew Erwood, Rima S. Rindler, Mustafa Motiwala, Sonia Ajmera, Brandy Vaughn, Paul Klimo Jr. and Joshua J. Chern
The authors evaluated the operative outcomes of children presenting with sterile abdominal pseudocysts related to ventriculoperitoneal shunt treatment. They found that shunts can be safely replaced in the abdomen in select patients. This is a simpler treatment than placing the shunt in the atrium or pleura and has fewer complications.
In this study the authors attempted to investigate cognitive function in the presurgical phase of pediatric patients with moyamoya disease with no apparent brain lesions. The results showed how cerebral hypoperfusion relates to cognitive decline.
Authors:Benjamin Davidson, Nathan Schoen, Shaina Sedighim, Renée Haldenby, Blythe Dalziel, Sara Breitbart, Darcy Fehlings, Golda Milo-Manson, Unni G. Narayanan, James M. Drake and George M. Ibrahim
The authors systematically reviewed published studies involving selective dorsal rhizotomy (SDR) and/or intrathecal baclofen (ITB) in patients with cerebral palsy (CP) who cannot walk. Traditionally SDR has been used mostly for children with moderate CP, who can walk. There is a growing interest in helping patients with severe CP using SDR, as it is less risky than ITB. In this study the authors show a need for further research, and that these treatments appear at least equal in this population.